CBS 2019
CBSMD教育中心
中 文

血流储备分数

Abstract

Recommended Article

Comparison of Coronary Computed Tomography Angiography, Fractional Flow Reserve, and Perfusion Imaging for Ischemia Diagnosis Coronary Flow Reserve in the Instantaneous Wave-Free Ratio/Fractional Flow Reserve Era: Too Valuable to Be Neglected Prognostic Implications of Plaque Characteristics and Stenosis Severity in Patients With Coronary Artery Disease Experimental basis of determining maximum coronary, myocardial, and collateral blood flow by pressure measurements for assessing functional stenosis severity before and after percutaneous transluminal coronary angioplasty Anatomical and Functional Computed Tomography for Diagnosing Hemodynamically Significant Coronary Artery Disease: A Meta-Analysis The Natural History of Nonculprit Lesions in STEMI: An FFR Substudy of the Compare-Acute Trial Long-term clinical outcome after fractional flow reserve-guided treatment in patients with angiographically equivocal left main coronary artery stenosis Coronary fractional flow reserve in bifurcation stenoses: what have we learned?
|<< 1 2 3 4 5 6 7 8 9 >>|

Original Research2014 Sep 1;84(3):406-13.

JOURNAL：Catheter Cardiovasc Interv. Article Link

Impact of myocardial supply area on the transstenotic hemodynamics as determined by fractional flow reserve

Shiono Y1 Kubo T, Tanaka A et al. Keywords: coronary angiography; fractional flow reserve; ischemic heart disease

ABSTRACT

OBJECTIVES - The aim of this study was to investigate the impact of myocardial area supplied by the coronary artery on fractional flow reserve (FFR).


BACKGROUND - Various factors other than the degree of epicardial stenosis influence the physiological significance of a coronary artery stenosis.

METHODS - A total of 296 coronary lesions in 217 patients were analyzed by quantitative coronary angiography and FFR. Myocardial area supplied by the coronary artery distal to the stenosis was evaluated by angiography using a modified version of the Alberta Provincial Project for Outcome Assessment in Coronary Heart Disease (APPROACH) score.

RESULTS - Percent diameter stenosis of the coronary lesion was 57 ± 15% (mean ± standard deviation). FFR <0.80 was seen in 132 (45%) lesions. FFR was significantly correlated with minimum lumen diameter (r = 0.584, P <0.001), percent diameter stenosis (r = -0.565, P <0.001), lesion length (r = -0.306, P <0.001), and myocardial supply area (r = -0.504, P <0.001). Multivariate logistic analysis demonstrated that minimum lumen diameter (odds ratio [OR] = 0.031, 95% confidence interval [CI] = 0.013-0.076, P < 0.001), lesion length (OR = 1.038, 95% CI = 1.009-1.069, P = 0.001), and myocardial supply area (OR = 1.113, 95% CI = 1.079-1.147, P <0.001) were independent determinants for FFR <0.80.

CONCLUSIONS - FFR, which is the index of physiological significance of coronary artery stenosis, is influenced by myocardial supply area distal to the stenosis as well as by its own minimal lumen diameter and lesion length.

© 2013 Wiley Periodicals, Inc.
>CBS CBS 2019

> CBS 2019 REGISTRATION

> CBS 2019 PROGRAM

> CBS 2019 CALL FOR SCIENCE

> CBS 2019 SPOTLIGHTS

 CBSMD

> CBSMD WEBSITE REGISTRATION

> EDUCATION CENTER

> RECOMMANDED PAPER

> TOP 10 RESEARCH PAPER

> PRE-READING

CBS 2019 CBS 2019 FACULTY Education Resource CBSMD Scientific Library
Copyright ⓒ CBS MD Nanjing China. All rights reserved. 京ICP备16025898号-11
联系我们| Top