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Acute Myocardial Infarction

Review Article | By Jeffrey L. Anderson, David A. Morrow

Acute myocardial infarction with or without ST-segment elevation (STEMI or non-STEMI) is a common cardiac emergency, with the potential for substantial morbidity and mortality. The management of acute myocardial infarction has improved dramatically over the past three decades and continues to evolve. This review focuses on the initial presentation and in-hospital management of type 1 acute myocardial infarction.

Quality of Care in Chinese Hospitals: Processes and Outcomes After ST-segment Elevation Myocardial Infarction

Clinical Trial | By Downing NS, Wang Y, Krumholz HM et al.

BACKGROUND - China has gaps in the quality of care provided to patients with ST-elevation myocardial infarction, but little is known about how quality varies between hospitals. METHODS AND RESULTS - Using nationally representative data from the China PEACE-Retrospective AMI Study, we characterized the quality of care for ST-elevation myocardial infarction at the hospital level and exami...

The China Patient-centered Evaluative Assessment of Cardiac Events (PEACE) Prospective Study of Percutaneous Coronary Intervention: Study Design

Clinical Trial | By Du X, Pi Y, the China PEACE Collaborative Group

BACKGROUND - The number of percutaneous coronary interventions (PCI) in China has increased more than 20-fold over the last decade. Consequently, there is a need for national-level information to characterize PCI indications and long-term patient outcomes, including health status, to understand and improve evolving practice patterns. OBJECTIVES - This nationwide prospective study of...

Rotational Atherectomy Followed by Drug-Coated Balloon Dilation for Left Main In-Stent Restenosis in the Setting of Acute Coronary Syndrome Complicated with Right Coronary Chronic Total Occlusion

Clinical Case Study | By Shiraishi J, Shoji K, Yanagiuchi T et al.

An 83-year-old man presented with recurrent acute coronary syndrome (ACS) at the left main coronary artery (LMCA) complicated with ostial chronic total occlusion (CTO) in the right coronary artery (RCA) (RCA-CTO). At the first LMCA-ACS approximately 1 year earlier, he had undergone LMCA-crossover stenting with a biolimus-eluting stent in the presence of RCA-CTO. At the second LMCA-ACS, we angiographically confirmed s...

Cutoff Value and Long-Term Prediction of Clinical Events by FFR Measured Immediately After Implantation of a Drug-Eluting Stent in Patients With Coronary Artery Disease: 1- to 3-Year Results From the DKCRUSH VII Registry Study

Clinical Trial | By Li SJ, Ge Z, Chen SL et al.

BACKGROUND - FFR immediately after a DES implantation correlates with clinical events. However, the cutoff of post-DES FFR for predicting long-term clinical events remains understudied. METHODS - Between May 2012 and September 2013, a total of 1,476 patients who had FFR <0.8 at maxim...

The SABRE Trial (Sirolimus Angioplasty Balloon for Coronary In-Stent Restenosis): Angiographic Results and 1-Year Clinical Outcomes

Clinical Trial | By Verheye S, Vrolix M, Kumsars I et al.

OBJECTIVES - The aim of this first-in-human study was to assess the safety and effectiveness of the Virtue sirolimus-eluting balloon in a cohort of patients with in-stent restenosis (ISR). BACKGROUND - Angioplasty balloons coated with the cytotoxic drug paclitaxel have been widely used for ISR treatment. The Virtue angioplasty balloon (Caliber Thera...

Coronary Catheterization and Percutaneous Coronary Intervention in China: 10-Year Results From the China PEACE-Retrospective CathPCI Study

Clinical Trial | By Zheng X, Curtis JP, China PEACE Collaborative Gro

IMPORTANCE - The use of coronary catheterization and percutaneous coronary intervention (PCI) is increasing in China, but, to date, there are no nationally representative assessments of the quality of care and outcomes in patients undergoing these procedures. OBJECTIVE - To assess the quality of care and outcomes of patients undergoing coronary catheterization and P...

Contemporary use of drug-coated balloons in coronary artery disease: Where are we now?

Review Article | By Picard F, Doucet S, Asgar AW

The drug-coated balloon (DCB) has emerged as an additional tool in the arsenal of interventional cardiology devices; it delivers antiproliferative drugs to local arterial tissue by single prolonged coated balloon angioplasty inflation, and prevents restenosis, leaving no implant behind. This strategy theoretically decreases the risk of late inflammatory response to device components, without preventing positive remodelling. DCBs, whe...

Clinical Outcomes and Cost-Effectiveness of Fractional Flow Reserve-Guided Percutaneous Coronary Intervention in Patients With Stable Coronary Artery Disease: Three-Year Follow-Up of the FAME 2 Trial (Fractional Flow Reserve Versus Angiography for Multivessel Evaluation)

Clinical Trial | By Fearon WF, Nishi T, FAME 2 Trial Investigators

BACKGROUND - Previous studies found that percutaneous coronary intervention (PCI) does not improve outcome compared with medical therapy (MT) in patients with stable coronary artery disease, but PCI was guided by angiography alone. FAME 2 trial (Fractional Flow Reserve Versus Angiography for Multivessel Evaluation) compared PCI guided by fractional flow reserve with best MT in patients with stable coronary arter...

Anatomical plaque and vessel characteristics are associated with hemodynamic indices including fractional flow reserve and coronary flow reserve: A prospective exploratory intravascular ultrasound analysis

Clinical Trial | By Brown AJ, Giblett JP, Hoole SP et al.

OBJECTIVES - To assess the relationship between anatomical form and physiological function in atherosclerotic coronary arteries. BACKGROUND - Although adverse cardiovascular events are predicted by plaque morphology or invasively-derived hemodynamic indices, the link between these important prognostic measures remains unexplored. METHODS - P...

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Original Research 785
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Clinical Trial 415
Perspective 9
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2017 8
2016 2

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N Engl J Med. 1
JAMA Intern Med. 1
JACC Cardiovasc Interv. 3
J Am Heart Assoc. 1
Int J Cardiol. 1
Int Heart J. 1
Catheter Cardiovasc Interv. 1
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