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急性冠脉综合征

科研文章

荐读文献

Improvement of Clinical Outcome in Patients With ST-Elevation Myocardial Infarction Between 1999 And 2016 in China : The Prospective, Multicenter Registry MOODY Study Contemporary Diagnosis and Management of Patients With Myocardial Infarction in the Absence of Obstructive Coronary Artery Disease: A Scientific Statement From the American Heart Association Efficacy and Safety of Low-Dose Colchicine after Myocardial Infarction Mortality in STEMI patients without standard modifiable risk factors: a sex-disaggregated analysis of SWEDEHEART registry data Optimal Timing of Intervention in NSTE-ACS Without Pre-Treatment The EARLY Randomized Trial Early Natural History of Spontaneous Coronary Artery Dissection Effect of a Restrictive vs Liberal Blood Transfusion Strategy on Major Cardiovascular Events Among Patients With Acute Myocardial Infarction and Anemia: The REALITY Randomized Clinical Trial Nonculprit Lesion Myocardial Infarction Following Percutaneous Coronary Intervention in Patients With Acute Coronary Syndrome Long-Term Outcomes of Patients With Late Presentation of ST-Segment Elevation Myocardial Infarction Relations between implementation of new treatments and improved outcomes in patients with non-ST-elevation myocardial infarction during the last 20 years: experiences from SWEDEHEART registry 1995 to 2014

Review Article2021 Jun 4;PP.

JOURNAL:IEEE Trans Med Imaging. Article Link

Dynamic Myocardial Ultrasound Localization Angiography

P Cormier, J Poree, C Bourquin et al. Keywords: dynamic myocardial ultrasound localization angiography

ABSTRACT

Dynamic Myocardial Ultrasound Localization Angiography (MULA) is an ultrasound-based imaging modality destined to enhance the diagnosis and treatment monitoring of coronary pathologies. Current diagnosis methods of coronary artery disease focus on the observation of vessel narrowing in the coronary vasculature to assess the organ’s condition. However, we would strongly benefit from mapping and measuring flow from intramyocardial arterioles and capillaries as they are the direct vehicle of the myocardium blood income. With the advent of ultrafast ultrasound scanners, imaging modalities based on the localization and tracking of injected microbubbles allow for the subwavelength resolution imaging of an organ’s vasculature. Yet, the application of these vascular imaging modalities relies on an accumulation of cine loops of a region of interest undergoing no or minimal tissue motion. This work introduces the MULA framework that combines 1) the mapping of the dynamics of the microvascular flow using an ultrasound sequence triggered by the electrocardiogram with a 2) novel Lagrangian beamformer based on non-rigid motion registration algorithm to form images directly in the myocardium’s material coordinates and thus correcting for the large myocardial motion and deformation. Specifically, we show that this framework enables the non-invasive imaging of the angioarchitecture and dynamics of intramyocardial flow in vessels as small as a few tens of microns in the rat’s beating heart in vivo.