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动脉粥样硬化性心血管疾病预防

科研文章

荐读文献

Coronary calcification in the diagnosis of coronary artery disease Stage-dependent differential effects of interleukin-1 isoforms on experimental atherosclerosis Sleep quality and risk of coronary heart disease-a prospective cohort study from the English longitudinal study of ageing Primary Prevention of Sudden Cardiac Death In patients with stable coronary heart disease, low-density lipoprotein-cholesterol levels < 70 mg/dL and glycosylated hemoglobin A1c < 7% are associated with lower major cardiovascular events High-risk plaque detected on coronary CT angiography predicts acute coronary syndromes independent of significant stenosis in acute chest pain: results from the ROMICAT-II trial From Focal Lipid Storage to Systemic Inflammation Identifying coronary artery disease patients at risk for sudden and/or arrhythmic death: remaining limitations of the electrocardiogram Effect of Evolocumab on Complex Coronary Disease Requiring Revascularization Simple Electrocardiographic Measures Improve Sudden Arrhythmic Death Prediction in Coronary Disease

Review Article1999 Jan 14;340(2):115-26.

JOURNAL:N Engl J Med. Article Link

Atherosclerosis — An Inflammatory Disease

Ross R Keywords: atherosclerosis; inflammatory disease

First 100 Words

Atherosclerosis is an inflammatory disease. Because high plasma concentrations of cholesterol, in particular those of low-density lipoprotein (LDL) cholesterol, are one of the principal risk factors for atherosclerosis,1 the process of atherogenesis has been considered by many to consist largely of the accumulation of lipids within the artery wall; however, it is much more than that. Despite changes in lifestyle and the use of new pharmacologic approaches to lower plasma cholesterol concentrations,2,3 cardiovascular disease continues to be the principal cause of death in the United States, Europe, and much of Asia.4,5 In fact, the lesions of atherosclerosis represent . . .