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Systematic Review for the 2018 AHA/ACC/AACVPR/AAPA/ABC/ACPM/ADA/AGS/APhA/ASPC/NLA/PCNA Guideline on the Management of Blood Cholesterol: A Report of the American College of Cardiology/American Heart Association Task Force on Clinical Practice Guidelines Effects of clopidogrel vs. prasugrel vs. ticagrelor on endothelial function, inflammatory parameters, and platelet function in patients with acute coronary syndrome undergoing coronary artery stenting: a randomized, blinded, parallel study Refractory Angina: From Pathophysiology to New Therapeutic Nonpharmacological Technologies Mechanisms and diagnostic evaluation of persistent or recurrent angina following percutaneous coronary revascularization Large-Bore Radial Access for Complex PCI: A Flash of COLOR With Some Shades of Grey Development and validation of a simple risk score to predict 30-day readmission after percutaneous coronary intervention in a cohort of medicare patients Systems of Care for ST-Segment–Elevation Myocardial Infarction: A Policy Statement From the American Heart Association Novel functions of macrophages in the heart: insights into electrical conduction, stress, and diastolic dysfunction No causal effects of plasma homocysteine levels on the risk of coronary heart disease or acute myocardial infarction: A Mendelian randomization study Pulmonary Artery Pressure-Guided Management of Patients With Heart Failure and Reduced Ejection Fraction

ConsensusOctober 10, 2017, Volume 136, Issue 15

JOURNAL:Circulation. Article Link

Contemporary Management of Cardiogenic Shock: A Scientific Statement From the American Heart Association

AHA Scientific Statements Keywords: AHA Scientific Statements; delivery of health care; disease management; shock, cardiogenic

ABSTRACT

Cardiogenic shock is a high-acuity, potentially complex, and hemodynamically diverse state of end-organ hypoperfusion that is frequently associated with multisystem organ failure. Despite improving survival in recent years, patient morbidity and mortality remain high, and there are few evidence-based therapeutic interventions known to clearly improve patient outcomes. This scientific statement on cardiogenic shock summarizes the epidemiology, pathophysiology, causes, and outcomes of cardiogenic shock; reviews contemporary best medical, surgical, mechanical circulatory support, and palliative care practices; advocates for the development of regionalized systems of care; and outlines future research priorities.