CBS 2019
CBSMD教育中心
中 文

Other Relevant Articles

Abstract

Recommended Article

Future of Personalized Cardiovascular Medicine Major trials in coronary intervention from 2018 Association of Coronary Anatomical Complexity With Clinical Outcomes After Percutaneous or Surgical Revascularization in the Veterans Affairs Clinical Assessment Reporting and Tracking Program The Prognostic Value of Exercise Echocardiography After Percutaneous Coronary Intervention Guiding Principles for Chronic Total Occlusion Percutaneous Coronary Intervention Novel functions of macrophages in the heart: insights into electrical conduction, stress, and diastolic dysfunction Post-Stroke Cardiovascular Complications and Neurogenic Cardiac Injury: JACC State-of-the-Art Review Randomized Comparison Between Radial and Femoral Large-Bore Access for Complex Percutaneous Coronary Intervention

Original ResearchVolume 74, Issue 19, November 2019

JOURNAL:J Am Coll Cardiol. Article Link

A Novel Algorithm for Treating Chronic Total Coronary Artery Occlusion

H Tanaka, E Tsuchikane, T Muramatsu et al. Keywords: algorithm; chronic total occlusion; guidewire manipulation time; PCI

ABSTRACT


BACKGROUND - Guidewire manipulation time is rarely used in chronic total occlusion (CTO) percutaneous coronary intervention (PCI) strategies.

 

OBJECTIVES - This study sought to develop an algorithm based on angiographic characteristics and guidewire manipulation time.

 

METHODS - This study assessed 5,843 patients undergoing CTO PCI between January 2014 and December 2017 and enrolled in the Japanese CTO-PCI expert registry and analyzed their CTO-PCI strategies, procedural outcomes, and guidewire manipulation time.

 

RESULTS - Primary retrograde approach was performed on 1,562 patients. The average Japanese CTO score of primary antegrade approach and primary retrograde approach were 1.7 ± 1.1 and 2.3 ± 1.1, respectively (p < 0.001). The overall guidewire and technical success rates were 92.8% and 90.6%, respectively. Median guidewire manipulation time of guidewire success and failure were 56 min (interquartile range [IQR]: 22 to 111 min) and 176 min (IQR: 130 to 229 min), respectively. Median successful guidewire crossing time of single wiring and parallel wiring in the antegrade alone were 23 min (IQR: 11 to 44 min) and 60 min (IQR: 36 to 97 min), and rescue retrograde approach and primary retrograde approach were 126 min (IQR: 87 to 174 min) and 107 min (IQR: 70 to 161 min), respectively (p < 0.001). Significant predictors for antegrade guidewire failure in primary antegrade approach, which were reattempt, CTO length of 20 mm, and no stump, did not predict guidewire failure after collateral channel crossing in primary retrograde approach.

 

CONCLUSIONS - Results from a large registry with information on guidewire manipulation time as well as CTO characteristics suggest a redefinition of the current strategy algorithms.