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ASCVD Prevention

Abstract

Recommended Article

Plaque Rupture, compared to Plaque Erosion, is associated with Higher Level of Pan-coronary Inflammation Regional Heterogeneity in the Coronary Vascular Response in Women With Chest Pain and Nonobstructive Coronary Artery Disease Prognostic implications of ischemia with nonobstructive coronary arteries (INOCA): Understanding risks for improving treatment Coronary Artery Plaque Characteristics Associated With Adverse Outcomes in the SCOT-HEART Study Comprehensive Investigation of Circulating Biomarkers and their Causal Role in Atherosclerosis-related Risk Factors and Clinical Events Autologous CD34+ Stem Cell Therapy Increases Coronary Flow Reserve and Reduces Angina in Patients With Coronary Microvascular Dysfunction Apolipoprotein A-V is a potential target for treating coronary artery disease: evidence from genetic and metabolomic analyses Relationship Between Coronary Artery Calcium and Atherosclerosis Progression Among Patients With Suspected Coronary Artery Disease

Review Article1999 Jan 14;340(2):115-26.

JOURNAL:N Engl J Med. Article Link

Atherosclerosis — An Inflammatory Disease

Ross R Keywords: atherosclerosis; inflammatory disease

First 100 Words

Atherosclerosis is an inflammatory disease. Because high plasma concentrations of cholesterol, in particular those of low-density lipoprotein (LDL) cholesterol, are one of the principal risk factors for atherosclerosis,1 the process of atherogenesis has been considered by many to consist largely of the accumulation of lipids within the artery wall; however, it is much more than that. Despite changes in lifestyle and the use of new pharmacologic approaches to lower plasma cholesterol concentrations,2,3 cardiovascular disease continues to be the principal cause of death in the United States, Europe, and much of Asia.4,5 In fact, the lesions of atherosclerosis represent . . .