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Disturbed shear stress promotes atherosclerosis through TRIM21-regulated MAPK6 degradation and consequent endothelial inflammation Lowering systolic blood pressure to less than 120 mm Hg versus less than 140 mm Hg in patients with high cardiovascular risk with and without diabetes or previous stroke: an open-label，blinded-outcome，randomised trial
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Clinical TrialSeptember 23, 2018

JOURNAL：N Engl J Med. Article Link

Transcatheter Mitral-Valve Repair in Patients with Heart Failure

Stone GW, Lindenfeld J, COAPT Investigators et al. Keywords: transcatheter mitral-valve repair; heart failure; mitral regurgitation; left ventricular dysfunction; clinical outcome

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