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Extended antiplatelet therapy with clopidogrel alone versus clopidogrel plus aspirin after completion of 9- to 12-month dual antiplatelet therapy for acute coronary syndrome patients with both high bleeding and ischemic risk. Rationale and design of the OPT-BIRISK double-blinded, placebo-controlled randomized trial Association of Effective Regurgitation Orifice Area to Left Ventricular End-Diastolic Volume Ratio With Transcatheter Mitral Valve Repair OutcomesA Secondary Analysis of the COAPT Trial Transcatheter Aortic Valve Replacement in Low-Risk Patients With Symptomatic Severe Bicuspid Aortic Valve Stenosis Transcatheter Aortic Valve Replacement: Role of Multimodality Imaging in Common and Complex Clinical Scenarios Randomized Evaluation of TriGuard 3 Cerebral Embolic Protection After Transcatheter Aortic Valve Replacement: REFLECT II Percutaneous Coronary Intervention Using Drug-Eluting Stents Versus Coronary Artery Bypass Grafting for Unprotected Left Main Coronary Artery Stenosis: A Meta-Analysis of Randomized Trials 2020 ACC Expert Consensus Decision Pathway on Management of Conduction Disturbances in Patients Undergoing Transcatheter Aortic Valve Replacement A Report of the American College of Cardiology Solution Set Oversight Committee MINOCA: a heterogenous group of conditions associated with myocardial damage Evolution of antithrombotic therapy in patients undergoing percutaneous coronary intervention: a 40-year journey Balloon Aortic Valvuloplasty as a Bridge to Aortic Valve Replacement: A Contemporary Nationwide Perspective

Review Article2015;11 Suppl V:V59-63.

JOURNAL:EuroIntervention. Article Link

Coronary fractional flow reserve in bifurcation stenoses: what have we learned?

Lee JM, Koo BK, Kumsars I et al. Keywords: fractional flow reserve; percutaneous coronary intervention; Coronary bifurcation; side branch

ABSTRACT


Fractional flow reserve (FFR) is a useful tool for the evaluation of coronary bifurcation lesions. FFR can guide treatment strategy, simplify the procedure and reduce unnecessary complex interventions. However, the application of FFR to complex bifurcation lesions requires a comprehensive understanding of its roles and potential pitfalls. Furthermore, FFR should be interpreted in the context of complex bifurcation anatomy and physiology rather than as a simple number. Finally, it should be recalled that the ischaemic burden is more important than the presence of ischaemia, and the risk/benefit of a complex intervention should be incorporated into the treatment decision after FFR measurement.