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Will Pulmonary Artery Denervation Really Have a Place in the Armamentarium of the Pulmonary Hypertension Specialist? Validation of bifurcation DEFINITION criteria and comparison of stenting strategies in true left main bifurcation lesions Long-term secondary prevention of cardiovascular disease with a Mediterranean diet and a low-fat diet (CORDIOPREV): a randomised controlled trial High-Resolution Cardiac Magnetic Resonance Imaging Techniques for the Identification of Coronary Microvascular Dysfunction Diagnostic Performance of Angiogram-Derived Fractional Flow Reserve: A Pooled Analysis of 5 Prospective Cohort Studies Intravascular optical coherence tomography Patient and Hospital Characteristics of Mitral Valve Surgery in the United States Angiography Alone Versus Angiography Plus Optical Coherence Tomography to Guide Percutaneous Coronary Intervention Outcomes From the Pan-London PCI Cohort New Volumetric Analysis Method for Stent Expansion and its Correlation With Final Fractional Flow Reserve and Clinical Outcome An ILUMIEN I Substudy Active and Passive Vaccination for Pulmonary Arterial Hypertension: A Novel Therapeutic Paradigm

Review Article2015;11 Suppl V:V59-63.

JOURNAL:EuroIntervention. Article Link

Coronary fractional flow reserve in bifurcation stenoses: what have we learned?

Lee JM, Koo BK, Kumsars I et al. Keywords: fractional flow reserve; percutaneous coronary intervention; Coronary bifurcation; side branch

ABSTRACT


Fractional flow reserve (FFR) is a useful tool for the evaluation of coronary bifurcation lesions. FFR can guide treatment strategy, simplify the procedure and reduce unnecessary complex interventions. However, the application of FFR to complex bifurcation lesions requires a comprehensive understanding of its roles and potential pitfalls. Furthermore, FFR should be interpreted in the context of complex bifurcation anatomy and physiology rather than as a simple number. Finally, it should be recalled that the ischaemic burden is more important than the presence of ischaemia, and the risk/benefit of a complex intervention should be incorporated into the treatment decision after FFR measurement.