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Comparative efficacy of two paclitaxel-coated balloons with different excipient coatings in patients with coronary in-stent restenosis: A pooled analysis of the Intracoronary Stenting and Angiographic Results: Optimizing Treatment of Drug Eluting Stent In-Stent Restenosis 3 and 4 trials Microvascular disease in chronic thromboembolic pulmonary hypertension: a role for pulmonary veins and systemic vasculature Updated clinical classification of pulmonary hypertension Coronary Microcirculation Downstream Non-Infarct-Related Arteries in the Subacute Phase of Myocardial Infarction: Implications for Physiology-Guided Revascularization Treatment of calcified coronary lesions with Palmaz-Schatz stents. An intravascular ultrasound study Lesion-Specific and Vessel-Related Determinants of Fractional Flow Reserve Beyond Coronary Artery Stenosis Cardiotoxicity and Cardiac Monitoring Among Chemotherapy-Treated Breast Cancer Patients Characteristics of abnormal post-stent optical coherence tomography findings in hemodialysis patients Effect of low-density lipoprotein cholesterol on the geometry of coronary bifurcation lesions and clinical outcomes of coronary interventions in the J-REVERSE registry Coronary Flow Reserve in the Instantaneous Wave-Free Ratio/Fractional Flow Reserve Era: Too Valuable to Be Neglected

Review Article2015;11 Suppl V:V59-63.

JOURNAL:EuroIntervention. Article Link

Coronary fractional flow reserve in bifurcation stenoses: what have we learned?

Lee JM, Koo BK, Kumsars I et al. Keywords: fractional flow reserve; percutaneous coronary intervention; Coronary bifurcation; side branch

ABSTRACT


Fractional flow reserve (FFR) is a useful tool for the evaluation of coronary bifurcation lesions. FFR can guide treatment strategy, simplify the procedure and reduce unnecessary complex interventions. However, the application of FFR to complex bifurcation lesions requires a comprehensive understanding of its roles and potential pitfalls. Furthermore, FFR should be interpreted in the context of complex bifurcation anatomy and physiology rather than as a simple number. Finally, it should be recalled that the ischaemic burden is more important than the presence of ischaemia, and the risk/benefit of a complex intervention should be incorporated into the treatment decision after FFR measurement.