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Contemporary real-world outcomes of surgical aortic valve replacement in 141,905 low-risk, intermediate-risk, and high-risk patients The prevalence and importance of frailty in heart failure with reduced ejection fraction - an analysis of PARADIGM-HF and ATMOSPHERE rhACE2 Therapy Modifies Bleomycin-Induced Pulmonary Hypertension via Rescue of Vascular Remodeling The Objective Physical Activity and Cardiovascular Disease Health in Older Women (OPACH) Study The Management of Atrial Fibrillation in Heart Failure: An Expert Panel Consensus A trial to evaluate the effect of the sodium-glucose co-transporter 2 inhibitor dapagliflozin on morbidity and mortality in patients with heart failure and reduced left ventricular ejection fraction (DAPA-HF) Metabolic Interactions and Differences between Coronary Heart Disease and Diabetes Mellitus: A Pilot Study on Biomarker Determination and Pathogenesis Optical coherence tomography and intravascular ultrasound assessment of the anatomic size and wall thickness of a muscle bridge segment Circadian-Regulated Cell Death in Cardiovascular Diseases Cardiovascular Considerations in Caring for Pregnant Patients: A Scientific Statement From the American Heart Association
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EditorialFebruary 12, 2019 Vol 139, Issue 7

JOURNAL：Circulation. Article Link

Classification of Deaths in Cardiovascular Outcomes Trials Known Unknowns and Unknown Unknowns

Morrow DA, Wiviott SD. Keywords: cardivascular system; clinical study; trial design

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