CBS 2019
CBSMD教育中心
English

科学研究

科研文章

荐读文献

1-Year Outcomes After Edge-to-Edge Valve Repair for Symptomatic Tricuspid Regurgitation: Results From the TriValve Registry rhACE2 Therapy Modifies Bleomycin-Induced Pulmonary Hypertension via Rescue of Vascular Remodeling Updated Expert Consensus Statement on Platelet Function and Genetic Testing for Guiding P2Y12 Receptor Inhibitor Treatment in Percutaneous Coronary Intervention Transcatheter Aortic Valve Implantation Represents an Anti-Inflammatory Therapy Via Reduction of Shear Stress-Induced, Piezo-1-Mediated Monocyte Activation Reduced Apolipoprotein M and Adverse Outcomes Across the Spectrum of Human Heart Failure Percutaneous Left Atrial Appendage Closure for Stroke Prophylaxis in Patients With Atrial Fibrillation: 2.3-Year Follow-up of the PROTECT AF (Watchman Left Atrial Appendage System for Embolic Protection in Patients With Atrial Fibrillation) Trial Clinical Phenogroups in Heart Failure With Preserved Ejection Fraction: Detailed Phenotypes, Prognosis, and Response to Spironolactone Three vs twelve months of dual antiplatelet therapy after zotarolimus-eluting stents: the OPTIMIZE randomized trial ACC/AHA Versus ESC Guidelines on Dual Antiplatelet Therapy JACC Guideline Comparison: JACC State-of-the-Art Review Effect of SGLT2-Inhibitors on Epicardial Adipose Tissue: A Meta-Analysis

Original Research

JOURNAL:CBSMD Article Link

心肌桥

CBSMD

Pre-reading

心肌桥(MB)是指不正常覆盖在冠状动脉上的心肌带。心肌桥患者通常无症状,但这种异常生理结构与劳累性心绞痛、急性冠状动脉综合征、心律失常、晕厥,甚至心脏猝死相关。有关MB的病理生理学、发生率及预测因子、诊疗策略、影像学测量及对不同患者群预后的影响可参考如下文献:


2014年“Myocardial bridging: contemporary understanding of pathophysiology with implications for diagnostic and therapeutic strategies汇总了当代MB的病理生理学及诊疗策略。


2018年10月“Fractional flow reserve derived from CCTA may have a prognostic role in myocardial bridging”评估了经CCTA测量的cFFR在预测心肌桥患者中的价值。


2019年1月“The Prevalence of Myocardial Bridging Associated with Coronary Endothelial Dysfunction in Patients with Chest Pain and Non-Obstructive Coronary Artery Disease”揭示了MB在胸痛和非阻塞性CAD患者中的发生率(208名观察患者中有14.2%人 ),并指出心肌桥与该患者群的心外膜和微血管内皮功能异常相关。


2019年2月“Myocardial bridging of the left anterior descending coronary artery is associated with reduced myocardial perfusion reserve: a 13N-ammonia PET study”定量评价了覆盖在左前降支上的MB对左心室心肌灌注的影响。


2019年2月“Optical coherence tomography and intravascular ultrasound assessment of the anatomic size and wall thickness of a muscle bridge segment”通过OCT和IVUS明确心肌桥段的血管解剖结构。介绍与相邻的非MB段相比,MB段的冠状动脉既短又薄,解释这样的解剖结构可能造成支架置入术中严重冠状动脉穿孔频次的增加。


2019年3月Machine Learning Using CT-FFR Predicts Proximal Atherosclerotic Plaque Formation Associated With LAD Myocardial Bridging介绍了使用CT-FFR预测前降支心肌桥近端动脉粥样硬化斑块形成的可能。