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Disturbed shear stress promotes atherosclerosis through TRIM21-regulated MAPK6 degradation and consequent endothelial inflammation Lowering systolic blood pressure to less than 120 mm Hg versus less than 140 mm Hg in patients with high cardiovascular risk with and without diabetes or previous stroke: an open-label，blinded-outcome，randomised trial
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Clinical Trial2020 Aug 18;9(16):e015103.

JOURNAL：J Am Heart Assoc. Article Link

Effect of Luseogliflozin on Heart Failure With Preserved Ejection Fraction in Patients With Diabetes Mellitus

K Ejiri, T Miyoshi, MUSCAT‐HF Study Investigators. Keywords: B‐type natriuretic peptide; DM; HF; sodium‐glucose cotransporter 2 inhibitor

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