CBS 2019
CBSMD教育中心
English

科学研究

科研文章

荐读文献

Association Between Malignant Mitral Valve Prolapse and Sudden Cardiac Death: A Review Pathophysiology, diagnosis and new therapeutic approaches for ischemic mitral regurgitation Initial experience with percutaneous mitral valve repair in patients with cardiac amyloidosis Transcatheter Interventions for Tricuspid Valve Disease: What to Do and Who to Do it On Closure of Iatrogenic Atrial Septal Defect Following Transcatheter Mitral Valve Repair: The Randomized MITHRAS Trial Italian Society of Interventional Cardiology (GIse) Registry Of Transcatheter Treatment of Mitral Valve RegurgitaTiOn (GIOTTO): Impact of Valve Disease Etiology and Residual Mitral Regurgitation after MitraClip Implantation Percutaneous left atrial appendage occlusion: the Munich consensus document on definitions, endpoints, and data collection requirements for clinical studies Novel Transcatheter Mitral Valve Prosthesis for Patients With Severe Mitral Annular Calcification The Tricuspid Annular Plane Systolic Excursion to Systolic Pulmonary Artery Pressure Index: Association With All-Cause Mortality in Patients With Moderate or Severe Tricuspid Regurgitation Risk of Atrial Fibrillation According to Cancer Type: A Nationwide Population-Based Study

Clinical Trial2018 Jan 8. [Epub ahead of print]

JOURNAL:J Interv Cardiol. Article Link

Short-term and long-term clinical outcomes of rotational atherectomy in resistant chronic total occlusion

Huang WC, Teng HI, Chan WL et al. Keywords: calcification; chronic total occlusion; coronary artery disease; rotational atherectomy

ABSTRACT


OBJECTIVES - To evaluate the short- and long-term clinical outcomes of RA in CTO coronary intervention.


BACKGROUND The application of rotational atherectomy (RA) may improve the success rate of percutaneous recanalization of chronic total occlusion (CTO) with heavy calcification.


METHODS - From January 2011 to September 2014, we enrolled 285 patients with CTO who underwent successful percutaneous coronary intervention (PCI). Resistant CTO lesions were defined as those with heavy calcifications as well as those that no devices are able to pass after guide wire crossing.


RESULTS - All patients with resistant CTO lesions (n = 26) were successfully treated by RA without major complications, except 1 patient complicated with coronary perforation and treated by surgery successfully (success rate: RA group vs non-RA group: 96.2%, vs 89.5%, P = 0.038). Compared to the non-RA group, the patients in the RA group were older (P = 0.028), had higher J-CTO scores (P = 0.001), and needed longer stents (P = 0.001). All patients were followed up for a mean period of 3.4 ± 2.3 years, and the 1-year and long-term clinical outcomes of the RA group were excellent and comparable with those not receiving RA in multivariate analysis adjusted for multiple variables.


CONCLUSION - The treatment of RA is safe and feasible for resistant CTO lesions with heavy calcification. The short- and long-term clinical outcomes of the treatment of RA were excellent and comparable with those not needing RA for CTO PCI.


© 2018, Wiley Periodicals, Inc.