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Lowering systolic blood pressure to less than 120 mm Hg versus less than 140 mm Hg in patients with high cardiovascular risk with and without diabetes or previous stroke: an open-label,blinded-outcome,randomised trial Disturbed shear stress promotes atherosclerosis through TRIM21-regulated MAPK6 degradation and consequent endothelial inflammation

Clinical Trial2020 Sep 7;41(34):3239-3252.

JOURNAL:Eur Heart J. Article Link

Genetic dysregulation of endothelin-1 is implicated in coronary microvascular dysfunction

TJ Ford, D Corcoran, S Padmanabhan et al. Keywords: coronary microvascular dysfunction; endothelin-1; microvascular angina; precision medicine; single-nucleotide polymorphism; stable angina pectoris

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