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Outcomes in patients treated with ticagrelor or clopidogrel after acute myocardial infarction: experiences from SWEDEHEART registry Inhibition of Platelet Aggregation After Coronary Stenting in Patients Receiving Oral Anticoagulation Impact of bleeding during dual antiplatelet therapy in patients with coronary artery disease Feasibility and efficacy of the ultrashort side branch dedicated balloon in coronary bifurcation stenting A prospective, randomized, open-label trial of 6-month versus 12-month dual antiplatelet therapy after drug-eluting stent implantation in ST-elevation myocardial infarction: Rationale and design of the 10-Year Outcomes of Stents Versus Coronary Artery Bypass Grafting for Left Main Coronary Artery Disease Intravascular Imaging and 12-Month Mortality After Unprotected Left Main Stem PCI: An Analysis From the British Cardiovascular Intervention Society Database Bayesian Interpretation of the EXCEL Trial and Other Randomized Clinical Trials of Left Main Coronary Artery Revascularization Comprehensive Investigation of Circulating Biomarkers and their Causal Role in Atherosclerosis-related Risk Factors and Clinical Events Drug-eluting stent implantation in patients with acute coronary syndrome - the Activity of Platelets after Inhibition and Cardiovascular Events: Optical Coherence Tomography (APICE OCT) study

Clinical Case Study2018 Jan 1;19(1):116.

JOURNAL:Eur Heart J Cardiovasc Imaging. Article Link

In vivo comparison of lipid-rich plaque on near-infrared spectroscopy with histopathological analysis of coronary atherectomy specimens

Nishihira K, Asaumi Y, Kataoka Y et al. Keywords: atherectomy, coronary spectroscopy, near-infrared lipids

ABSTRACT


A 42-year-old man with angina pectoris was hospitalized to undergo percutaneous coronary intervention (PCI) for a significant stenosis in the mid-left anterior descending (LAD) coronary artery (Panel A). Optical coherence tomography (OCT) and near-infrared spectroscopy (NIRS) imaging at the arrowhead site identified the presence of lipid-rich plaque, exhibiting a high maximum 4-mm lipid core burden index (max-LCBI) with the value of 925 (Panels B and C; Supplementary data online, Video S1). Following PCI with directional coronary atherectomy (DCA), resection of the lipid-rich plaque was observed on OCT imaging (Panels D and D’; Supplementary data online, Video S2). Corresponding NIRS imaging demonstrated a marked reduction of yellow signals on chemogram accompanied by decrease in max-LCBI to 248 (Panel E,asterisk).