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Negative Risk Markers for Cardiovascular Events in the Elderly Long-term effects of intensive glucose lowering on cardiovascular outcomes Predictors of high residual gradient after transcatheter aortic valve replacement in bicuspid aortic valve stenosis Early Surgery or Conservative Care for Asymptomatic Aortic Stenosis A Combined Optical Coherence Tomography and Intravascular Ultrasound Study on Plaque Rupture, Plaque Erosion, and Calcified Nodule in Patients With ST-Segment Elevation Myocardial Infarction: Incidence, Morphologic Characteristics, and Outcomes After Percutaneous Coronary Intervention Rationale and design of a large-scale, app-based study to identify cardiac arrhythmias using a smartwatch: The Apple Heart Study The Evolution of β-Blockers in Coronary Artery Disease and Heart Failure (Part 1/5) 2019 Guidelines on Diabetes, Pre-Diabetes and Cardiovascular Diseases developed in collaboration with the EASD ESC Clinical Practice Guidelines Impact of Positive and Negative Lesion Site Remodeling on Clinical Outcomes : Insights From PROSPECT Colchicine Reduces Cardiovascular Events in Chronic Coronary Disease

Clinical Case Study2018 Jan 1;19(1):116.

JOURNAL:Eur Heart J Cardiovasc Imaging. Article Link

In vivo comparison of lipid-rich plaque on near-infrared spectroscopy with histopathological analysis of coronary atherectomy specimens

Nishihira K, Asaumi Y, Kataoka Y et al. Keywords: atherectomy, coronary spectroscopy, near-infrared lipids

ABSTRACT


A 42-year-old man with angina pectoris was hospitalized to undergo percutaneous coronary intervention (PCI) for a significant stenosis in the mid-left anterior descending (LAD) coronary artery (Panel A). Optical coherence tomography (OCT) and near-infrared spectroscopy (NIRS) imaging at the arrowhead site identified the presence of lipid-rich plaque, exhibiting a high maximum 4-mm lipid core burden index (max-LCBI) with the value of 925 (Panels B and C; Supplementary data online, Video S1). Following PCI with directional coronary atherectomy (DCA), resection of the lipid-rich plaque was observed on OCT imaging (Panels D and D’; Supplementary data online, Video S2). Corresponding NIRS imaging demonstrated a marked reduction of yellow signals on chemogram accompanied by decrease in max-LCBI to 248 (Panel E,asterisk).