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Disturbed shear stress promotes atherosclerosis through TRIM21-regulated MAPK6 degradation and consequent endothelial inflammation Lowering systolic blood pressure to less than 120 mm Hg versus less than 140 mm Hg in patients with high cardiovascular risk with and without diabetes or previous stroke: an open-label，blinded-outcome，randomised trial
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Guidelinehttps://academic.oup.com/eurheartj/advance-article/doi/10.1093/eurheartj/ehaa575/5898842

JOURNAL：Eur Heart J. Article Link

2020 ESC Guidelines for the management of acute coronary syndromes in patients presenting without persistent ST-segment elevation: The Task Force for the management of acute coronary syndromes in patients presenting without persistent ST-segment elevation of the European Society of Cardiology (ESC)

J-P Collet, H Thiele, E Barbato et al. Keywords: ACS without persistent ST-segment elevation; Guidelines; acute cardiac care; angioplasty; anticoagulation; antiplatelet; apixaban; aspirin; atherothrombosis; betablockers; bleedings; bivalirudin; CABG; cangrelor; chest pain unit; clopidogrel; dabigatran; diabetes; DAPT; early invasive strategy; edoxaban; enoxaparin; fondaparinux; glycoprotein IIb/IIIa inhibitors; heparin; high-sensitivity troponin; MINOCA; myocardial ischaemia; MI; nitrates; platelet inhibition; prasugrel; revascularization; rhythm monitoring; rivaroxaban; stent; ticagrelor; triple therapy; unstable angina

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