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Apolipoprotein A-V is a potential target for treating coronary artery disease: evidence from genetic and metabolomic analyses Pulmonary Artery Denervation Using Catheter based Ultrasonic Energy Impact of myocardial supply area on the transstenotic hemodynamics as determined by fractional flow reserve Physiologic Characteristics and Clinical Outcomes of Patients With Discordance Between FFR and iFR A Case of Pulmonary Hypertension Associated with Idiopathic Hypereosinophilic Syndrome Transcatheter Aortic Valve Implantation Represents an Anti-Inflammatory Therapy Via Reduction of Shear Stress–Induced, Piezo-1–Mediated Monocyte Activation Pulmonary arterial hypertension in congenital heart disease: an epidemiologic perspective from a Dutch registry The right ventricle in pulmonary hypertension Refined balloon pulmonary angioplasty for inoperable patients with chronic thromboembolic pulmonary hypertension Survival prospects of treatment naïve patients with Eisenmenger: a systematic review of the literature and report of own experience

Review Article2017 Nov 14;70(20):2536-2551.

JOURNAL:J Am Coll Cardiol. Article Link

Cardiovascular Complications of Cancer Therapy: Best Practices in Diagnosis, Prevention, and Management: Part 1

Chang HM, Moudgil R, Yeh ETH et al. Keywords: cancer therapy; cardiomyopathy; cardiovascular complication; ischemia

ABSTRACT


Modern cancer therapy has successfully cured many cancers and converted a terminal illness into a chronic disease. Because cancer patients often have coexisting heart diseases, expert advice from cardiologists will improve clinical outcome. In addition, cancer therapy can also cause myocardial damage, induce endothelial dysfunction, and alter cardiac conduction. Thus, it is important for practicing cardiologists to be knowledgeable about the diagnosis, prevention, and management of the cardiovascular complications of cancer therapy. In this first part of a 2-part review, we will review cancer therapy-induced cardiomyopathy and ischemia. This review is based on a MEDLINE search of published data, published clinical guidelines, and best practices in major cancer centers. With the number of cancer survivors expanding quickly, the time has come for cardiologists to work closely with cancer specialists to prevent and treat cancer therapy-induced cardiovascular complications.