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2019 Guidelines on Diabetes, Pre-Diabetes and Cardiovascular Diseases developed in collaboration with the EASD ESC Clinical Practice Guidelines Active factor XI is associated with the risk of cardiovascular events in stable coronary artery disease patients Membrane type 1 matrix metalloproteinase promotes LDL receptor shedding and accelerates the development of atherosclerosis Clinical and angiographic outcomes of patients treated with everolimus-eluting stents or first-generation Paclitaxel-eluting stents for unprotected left main disease Sex-Based Outcomes in Patients With a High Bleeding Risk After Percutaneous Coronary Intervention and 1-Month Dual Antiplatelet Therapy: A Secondary Analysis of the LEADERS FREE Randomized Clinical Trial Percutaneous Coronary Intervention of Left Main Disease: Pre- and Post-EXCEL (Evaluation of XIENCE Everolimus Eluting Stent Versus Coronary Artery Bypass Surgery for Effectiveness of Left Main Revascularization) and NOBLE (Nordic-Baltic-British Left Main Revascularization Study) Era Impact of SYNTAX Score on 10-Year Outcomes After Revascularization for Left Main Coronary Artery Disease Anthracycline Therapy Is Associated With Cardiomyocyte Atrophy and Preclinical Manifestations of Heart Disease When, where, and how to target vascular inflammation in the post-CANTOS era? Long-Term Outcomes of Different Two-Stent Techniques With Second-Generation Drug-Eluting Stents for Unprotected Left Main Bifurcation Disease: Insights From the FAILS-2 Study

Research Correspondence2018 May 14;11(9):915-917.

JOURNAL:JACC Cardiovasc Interv. Article Link

Impact of Off-Hours Versus On-Hours Primary Percutaneous Coronary Intervention on Myocardial Damage and Clinical Outcomes in ST-Segment Elevation Myocardial Infarction

Reinstadler SJ, Stiermaier T, Eitel C et al. Keywords: off-hours; on-hours; PPCI; myocardial damage; STEMI

ABSTRACT


There is an ongoing debate on potential differences in outcome between ST-segment elevation myocardial infarction (STEMI) patients presenting outside of usual hospital working hours (“off-hours”) compared with patients presenting during classical working hours (“on-hours”) (1,2). The aim of this study was to evaluate potential differences in the amount of salvaged myocardium and the extent of myocardial damage by applying cardiac magnetic resonance (CMR) imaging in a large contemporary cohort of STEMI patients.