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Sex Differences in Cardiovascular Pathophysiology: Why Women Are Overrepresented in Heart Failure With Preserved Ejection Fraction Myofibroblast Phenotype and Reversibility of Fibrosis in Patients With End-Stage Heart Failure Titration of Medical Therapy for Heart Failure With Reduced Ejection Fraction Prevalence and clinical implications of valvular calcification on coronary computed tomography angiography DAPT, Our Genome and Clopidogrel Intravascular Ultrasound to Guide Left Main Stem Intervention: A Sub-Study of the NOBLE Trial Two-Year Outcomes with a Magnetically Levitated Cardiac Pump in Heart Failure Feasibility of Coronary Access and Aortic Valve Reintervention in Low-Risk TAVR Patients From ACE Inhibitors/ARBs to ARNIs in Coronary Artery Disease and Heart Failure (Part 2/5) Intravascular ultrasound-guided vs angiography-guided drug-eluting stent implantation in complex coronary lesions: Meta-analysis of randomized trials

Research Correspondence2018 May 14;11(9):915-917.

JOURNAL:JACC Cardiovasc Interv. Article Link

Impact of Off-Hours Versus On-Hours Primary Percutaneous Coronary Intervention on Myocardial Damage and Clinical Outcomes in ST-Segment Elevation Myocardial Infarction

Reinstadler SJ, Stiermaier T, Eitel C et al. Keywords: off-hours; on-hours; PPCI; myocardial damage; STEMI

ABSTRACT


There is an ongoing debate on potential differences in outcome between ST-segment elevation myocardial infarction (STEMI) patients presenting outside of usual hospital working hours (“off-hours”) compared with patients presenting during classical working hours (“on-hours”) (1,2). The aim of this study was to evaluate potential differences in the amount of salvaged myocardium and the extent of myocardial damage by applying cardiac magnetic resonance (CMR) imaging in a large contemporary cohort of STEMI patients.