CBS 2019
CBSMD教育中心
English

科学研究

科研文章

荐读文献

Frailty and Bleeding in Older Adults Undergoing TAVR or SAVR: Insights From the FRAILTY-AVR Study The Objective Physical Activity and Cardiovascular Disease Health in Older Women (OPACH) Study Percutaneous Coronary Intervention vs Coronary Artery Bypass Grafting in Patients With Left Main Coronary Artery Stenosis: A Systematic Review and Meta-analysis The prevalence and importance of frailty in heart failure with reduced ejection fraction - an analysis of PARADIGM-HF and ATMOSPHERE Transcatheter Aortic Valve Replacement in Low-risk Patients With Bicuspid Aortic Valve Stenosis The Role of the Pericardium in Heart Failure: Implications for Pathophysiology and Treatment Cardio-Oncology: How New Targeted Cancer Therapies and Precision Medicine Can Inform Cardiovascular Discovery Serial intravascular ultrasound assessment of very late stent thrombosis after sirolimus-eluting stent placement Long-Term Outcomes of Anticoagulation for Bioprosthetic Valve Thrombosis Bridging the Gap Between Epigenetic and Genetic in PAH
|<<... 91 92 93 94 95 96 97 ...>>|

Clinical Trial2011 Apr;6(9):1037-45.

JOURNAL：EuroIntervention. Article Link

First-in-man evaluation of intravascular optical frequency domain imaging (OFDI) of Terumo: a comparison with intravascular ultrasound and quantitative coronary angiography

Okamura T, Onuma Y, Garcia-Garcia HM et al. Keywords: IVUS; stents; OCT; coronary imaging; optical frequency domain imaging

ABSTRACT

AIMS - The objective of this study is to evaluate the feasibility and safety of imaging human coronary arteries in vivo by optical frequency domain imaging (OFDI) in comparison to intravascular ultrasound (IVUS). OFDI has been recently developed to overcome the limitations of conventional time-domain optical coherence tomography (OCT), namely the need for proximal balloon occlusion. The Terumo-OFDI system is capable of acquiring images with high-speed automated pullback (up to 40 mm/sec) and requires only a short injection (3-4 sec) of small amount of x-ray contrast (9-16 ml).


METHODS AND RESULTS - Nineteen patients who underwent stent implantation were enrolled. IVUS/OFDI were performed before and after stenting. The incidences of any adverse event and angiographic adverse findings were recorded. Lumen area (LA) was measured by IVUS and OFDI at 1 mm intervals in the stented segments (n=19) as well as in the proximal, distal, and to-be-stented segments (n=40). In addition, lumen area in the stented segment was also measured by edge (E-) and video-densitometric (VD-) quantitative coronary angiography (QCA). The OFDI images were obtained without any adverse event related to imaging procedures. Post stenting (n=19), minimal LA (MLA) measured by OFDI (5.84 ± 1.89 mm2) was larger than that of E-QCA (4.16 ± 1.46 mm2, p<0.001) and VD-QCA (4.92 ± 1.55 mm2, p<0.05). It was smaller than IVUS-MLA (6.26 ± 2.01 mm2, N.S.) but the correlation between the two measurements was highly significant (R2=0.82, p<0.001).

CONCLUSIONS - The OFDI imaging is feasible both before and after stenting and has a promising safety profile. The OFDI provided clear high resolution images and robust lumen measurements.
>CBS CBS 2019

> CBS 2019

> CBS 2019 注册

> CBS 2019 会议日程

> CBS 2019 学术征集

> CBS 2019 热点

 CBSMD

> CBSMD 网站注册

> 教育中心

> 荐读文献

> Top 10 阅读文献

> 文献导读
CBS 2019 CBS 2019 主席团 教育中心 科研动态
Copyright ⓒ CBS MD Nanjing China. All rights reserved. 京ICP备16025898号-11
联系我们| Top