CBS 2019
CBSMD教育中心
English

科学研究

科研文章

荐读文献

Nocturnal thoracic volume overload and post-discharge outcomes in patients hospitalized for acute heart failure Optical coherence tomography and intravascular ultrasound assessment of the anatomic size and wall thickness of a muscle bridge segment Prevalence and Outcomes of Concomitant Aortic Stenosis and Cardiac Amyloidosis Long-Term Outcomes of Anticoagulation for Bioprosthetic Valve Thrombosis Extreme Levels of Air Pollution Associated With Changes in Biomarkers of Atherosclerotic Plaque Vulnerability and Thrombogenicity in Healthy Adults Plasma Ionized Calcium and Risk of Cardiovascular Disease: 106 774 Individuals from the Copenhagen General Population Study Association of Statin Use With All-Cause and Cardiovascular Mortality in US Veterans 75 Years and Older Burden of Cardiovascular Diseases in China, 1990-2016: Findings From the 2016 Global Burden of Disease Study Clinical Impact of Valvular Heart Disease in Elderly Patients Admitted for Acute Coronary Syndrome: Insights From the Elderly-ACS 2 Study Longitudinal Assessment of Vascular Function With Sunitinib in Patients With Metastatic Renal Cell Carcinoma

Clinical Trial2018 May 19. [Epub ahead of print]

JOURNAL:Cardiovasc Revasc Med. Article Link

Impact of different final optimization techniques on long-term clinical outcomes of left main cross-over stenting

Rigatelli G, Zuin M, Karamfilof K et al. Keywords: Angioplasty; Coronary angiography; Coronary artery disease; Interventional; Surgery

ABSTRACT


BACKGROUND - The optimal final optimization technique to be used in patients after Cross Over Left main stenting remains debatable.


AIM - We evaluate the impact of the post-optimization technique (POT), kissing balloon (KB) and the POT-side-POT techniques on both cardiovascular mortality and event-free survival in patients receiving left main (LM) cross-over stenting for an isolated/distal bifurcation LM disease.

METHODS - Clinical and instrumental records of 128 consecutive patients (102 males, mean age 73.39 ± 9.54 years old) with isolated distal/bifurcation LM disease and bypass surgery contraindications or refusal enrolled to receive LM cross-over stenting between the 1st January 2012 and the 1st January 2017 at two institutions: the Rovigo General Hospital (Rovigo, Italy) and the Alexandrovka Hospital University School of Medicine (Sofia, Bulgaria). Patients has been divided into three groups (POT, KB and POT-side-POT) according the optimal final optimization technique used while the 5-year cardiovascular mortality has been evaluated using the log-rank (Mantel-Cox) analysis.

RESULTS - Baseline angiographic characteristics of the LM disease were mostly equivalent among the three groups. Over a global follow-up of 61.03 ± 0.92 months, the rates of target vessel revascularization, acute myocardial infarction, and stent thrombosis, were not different among groups. Patients treated with POT had a slightly better long-term survival.

CONCLUSIONS - None of these optimization techniques appeared to have clearly better long-term outcomes after LM Cross-over stenting in our retrospective study. POT resulted in a slightly better survival compared to Pot-sid-POT and KB.

Copyright © 2018 Elsevier Inc. All rights reserved.