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The right ventricle in pulmonary hypertension Real-world clinical utility and impact on clinical decision-making of coronary computed tomography angiography-derived fractional flow reserve: lessons from the ADVANCE Registry Fractional flow reserve-guided PCI versus medical therapy in stable coronary disease Clinical Outcomes and Cost-Effectiveness of Fractional Flow Reserve-Guided Percutaneous Coronary Intervention in Patients With Stable Coronary Artery Disease: Three-Year Follow-Up of the FAME 2 Trial (Fractional Flow Reserve Versus Angiography for Multivessel Evaluation) Prognostic Implication of Thermodilution Coronary Flow Reserve in Patients Undergoing Fractional Flow Reserve Measurement Diagnosis of ischemia-causing coronary stenoses by noninvasive fractional flow reserve computed from coronary computed tomographic angiograms. Results from the prospective multicenter DISCOVER-FLOW Patient and Hospital Characteristics of Mitral Valve Surgery in the United States Relationship between fractional flow reserve value and the amount of subtended myocardium Independent Association of Lipoprotein(a) and Coronary Artery Calcification With Atherosclerotic Cardiovascular Risk Fractional Flow Reserve-Guided Multivessel Angioplasty in Myocardial Infarction

Original Research2018 Jul 23;11(14):1421-1422.

JOURNAL:JACC Cardiovasc Interv. Article Link

Coronary Artery Intraplaque Microvessels by Optical Coherence Tomography Correlate With Vulnerable Plaque and Predict Clinical Outcomes in Patients With Ischemic Angina

Xu T, Lin L, Chen SL et al. Keywords: Coronary Artery Intraplaque Microvessels; OCT; Vulnerable Plaque; Outcome; Ischemic Angina

ABSTRACT


Atherosclerosis is a chronic inflammatory disease characterized by increased requirements of oxygen supply with cells in the plaque, which will promote the invasion of the vessel wall by the vasa vasorum and lead to the formation of newly restructured microvessels (MVs) in the plaque. MV formation is reported to be correlated with the vulnerability of plaques. We analyzed the prevalence and clinical relevance of MVs in patients with coronary artery disease.