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Low shear stress induces endothelial reactive oxygen species via the AT1R/eNOS/NO pathway Prognostic implications of ischemia with nonobstructive coronary arteries (INOCA): Understanding risks for improving treatment Left main coronary artery compression in pulmonary hypertension Meta-Analysis of Death and Myocardial Infarction in the DEFINE-FLAIR and iFR-SWEDEHEART Trials OCT compared with IVUS in a coronary lesion assessment: the OPUS-CLASS study Covering our tracks – optical coherence tomography to assess vascular healing Updated clinical classification of pulmonary hypertension The EBC TWO Study (European Bifurcation Coronary TWO): A Randomized Comparison of Provisional T-Stenting Versus a Systematic 2 Stent Culotte Strategy in Large Caliber True Bifurcations Comparison of Coronary Intimal Plaques by Optical Coherence Tomography in Arteries With Versus Without Internal Running Vasa Vasorum Retrospective Comparison of Long-Term Clinical Outcomes Between Percutaneous Coronary Intervention and Medical Therapy in Stable Coronary Artery Disease With Gray Zone Fractional Flow Reserve - COMFORTABLE Retrospective Study

Original Research2018 Jul 23;11(14):1421-1422.

JOURNAL:JACC Cardiovasc Interv. Article Link

Coronary Artery Intraplaque Microvessels by Optical Coherence Tomography Correlate With Vulnerable Plaque and Predict Clinical Outcomes in Patients With Ischemic Angina

Xu T, Lin L, Chen SL et al. Keywords: Coronary Artery Intraplaque Microvessels; OCT; Vulnerable Plaque; Outcome; Ischemic Angina

ABSTRACT


Atherosclerosis is a chronic inflammatory disease characterized by increased requirements of oxygen supply with cells in the plaque, which will promote the invasion of the vessel wall by the vasa vasorum and lead to the formation of newly restructured microvessels (MVs) in the plaque. MV formation is reported to be correlated with the vulnerability of plaques. We analyzed the prevalence and clinical relevance of MVs in patients with coronary artery disease.