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Effect of low-density lipoprotein cholesterol on the geometry of coronary bifurcation lesions and clinical outcomes of coronary interventions in the J-REVERSE registry Developing a Mobile Application for Global Cardiovascular Education Coronary Atherosclerosis T1-Weighed Characterization With Integrated Anatomical Reference: Comparison With High-Risk Plaque Features Detected by Invasive Coronary Imaging Update on chronic thromboembolic pulmonary hypertension Long-term secondary prevention of cardiovascular disease with a Mediterranean diet and a low-fat diet (CORDIOPREV): a randomised controlled trial Prospective, large-scale multicenter trial for the use of drug-coated balloons in coronary lesions: The DCB-only All-Comers Registry Adaptive development of concomitant secondary mitral and tricuspid regurgitation after transcatheter aortic valve replacement Changes in Coronary Plaque Composition in Patients With Acute Myocardial Infarction Treated With High-Intensity Statin Therapy (IBIS-4): A Serial Optical Coherence Tomography Study Active and Passive Vaccination for Pulmonary Arterial Hypertension: A Novel Therapeutic Paradigm Diagnostic Performance of Angiogram-Derived Fractional Flow Reserve: A Pooled Analysis of 5 Prospective Cohort Studies

Original Research2018 Jul 23;11(14):1421-1422.

JOURNAL:JACC Cardiovasc Interv. Article Link

Coronary Artery Intraplaque Microvessels by Optical Coherence Tomography Correlate With Vulnerable Plaque and Predict Clinical Outcomes in Patients With Ischemic Angina

Xu T, Lin L, Chen SL et al. Keywords: Coronary Artery Intraplaque Microvessels; OCT; Vulnerable Plaque; Outcome; Ischemic Angina

ABSTRACT


Atherosclerosis is a chronic inflammatory disease characterized by increased requirements of oxygen supply with cells in the plaque, which will promote the invasion of the vessel wall by the vasa vasorum and lead to the formation of newly restructured microvessels (MVs) in the plaque. MV formation is reported to be correlated with the vulnerability of plaques. We analyzed the prevalence and clinical relevance of MVs in patients with coronary artery disease.