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Plaque composition by intravascular ultrasound and distal embolization after percutaneous coronary intervention Aspirin in the primary and secondary prevention of vascular disease: collaborative meta-analysis of individual participant data from randomised trials Derivation, Validation, and Prognostic Utility of a Prediction Rule for Nonresponse to Clopidogrel: The ABCD-GENE Score Meta-analysis of outcomes after intravascular ultrasound-guided versus angiography-guided drug-eluting stent implantation in 26,503 patients enrolled in three randomized trials and 14 observational studies Poor R-wave progression as a predictor of sudden cardiac death in general population and subjects with coronary artery disease A pragmatic approach to the use of inotropes for the management of acute and advanced heart failure: An expert panel consensus In acute HF and iron deficiency, IV ferric carboxymaltose reduced HF hospitalizations, but not CV death, at 1 y Relationship between intravascular ultrasound guidance and clinical outcomes after drug-eluting stents: the assessment of dual antiplatelet therapy with drug-eluting stents (ADAPT-DES) study Effects of Dapagliflozin on Symptoms, Function and Quality of Life in Patients with Heart Failure and Reduced Ejection Fraction: Results from the DAPA-HF Trial Clinical impact of intravascular ultrasound-guided chronic total occlusion intervention with zotarolimus-eluting versus biolimus-eluting stent implantation: randomized study

Original Research2018 Jul 23;11(14):1421-1422.

JOURNAL:JACC Cardiovasc Interv. Article Link

Coronary Artery Intraplaque Microvessels by Optical Coherence Tomography Correlate With Vulnerable Plaque and Predict Clinical Outcomes in Patients With Ischemic Angina

Xu T, Lin L, Chen SL et al. Keywords: Coronary Artery Intraplaque Microvessels; OCT; Vulnerable Plaque; Outcome; Ischemic Angina

ABSTRACT


Atherosclerosis is a chronic inflammatory disease characterized by increased requirements of oxygen supply with cells in the plaque, which will promote the invasion of the vessel wall by the vasa vasorum and lead to the formation of newly restructured microvessels (MVs) in the plaque. MV formation is reported to be correlated with the vulnerability of plaques. We analyzed the prevalence and clinical relevance of MVs in patients with coronary artery disease.