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荐读文献
Management of Acute Myocardial Infarction During the COVID-19 Pandemic
CSC Expert Consensus on Principles of Clinical Management of Patients with Severe Emergent Cardiovascular Diseases during the COVID-19 Epidemic
ACC临床简报:新型冠状病毒对心脏的影响(2019-nCoV)
SCAI Expert Consensus Statement Update on Best Practices for Transradial Angiography and Intervention
Empagliflozin and Progression of Kidney Disease in Type 2 Diabetes
Clinical Trial | By Wanner C, Inzucchi SE, EMPA-REG OUTCOME Investigators.
BACKGROUND - Diabetes confers an increased risk of adverse cardiovascular and renal events. In the EMPA-REG OUTCOME trial, empagliflozin, a sodium-glucose cotransporter 2 inhibitor, reduced the risk of major adverse cardiovascular events in patients with type 2 diabetes at high risk for cardiovascular events. We wanted to determine the long-term renal effects of empagliflozin, an analysis that was a prespecified component of the...
Canagliflozin and Cardiovascular and Renal Events in Type 2 Diabetes
Clinical Trial | By Neal B, Perkovic V, CANVAS Program Collaborative Group.
BACKGROUND - Canagliflozin is a sodium-glucose cotransporter 2 inhibitor that reduces glycemia as well as blood pressure, body weight, and albuminuria in people with diabetes. We report the effects of treatment with canagliflozin on cardiovascular, renal, and safety outcomes. METHODS - The CANVAS Program integrated data from two trials involving a total of 10,142 participants with type 2 di...
Canagliflozin and Renal Outcomes in Type 2 Diabetes and Nephropathy
Clinical Trial | By Perkovic V, Jardine MJ, CREDENCE Trial Investigators.
BACKGROUND - Type 2 diabetes mellitus is the leading cause of kidney failure worldwide, but few effective long-term treatments are available. In cardiovascular trials of inhibitors of sodium-glucose cotransporter 2 (SGLT2), exploratory results have suggested that such drugs may improve renal outcomes in patients with type 2 diabetes. METHODS - In this double-blind, randomized trial, we assigned pat...
Original Research | By H Bueno, X Rossello, SJ Pocock et al.
BACKGROUND - The relationship between in-hospital coronary revascularization rate (CRR) and post-discharge mortality rates in survivors of non–ST-segment elevation acute coronary syndrome (NSTE-ACS) at a system level is unclear. OBJECTIVES- The purpose of this study was to evaluate CRR and 2-year post-discharge mortality rate (2YMR) in NSTE-ACS. METHOD...
Transcatheter Versus Surgical Aortic Valve Replacement in Low-Risk Patients
Review Article | By DKolte, GJ Vlahakes, IF Palacios et al.
BACKGROUND- Transcatheter aortic valve replacement (TAVR) has emerged as a safe and effective therapeutic option for patients with severe aortic stenosis (AS) who are at prohibitive, high, or intermediate risk for surgical aortic valve replacement (SAVR). However, in low-risk patients, SAVR remains the standard therapy in current clinical practice. OBJECTIVES - This study sought to perfo...
Incidence and Outcomes of Surgical Bailout During TAVR : Insights From the STS/ACC TVT Registry
Original Research | By AM Pineda, JK Harrison, NS Kleiman et al.
OBJECTIVES - The aim of this study was to evaluate the incidence and outcomes of surgical bailout during transcatheter aortic valve replacement (TAVR). BACKGROUND- The incidence and outcomes of unplanned conversion to open heart surgery, or “surgical bailout,” during TAVR are not well characterized. METHODS- Data from the Society of Thoracic Surgeons/American College of C...
Original Research | By Nassif ME, Windsor S, DEFINE-HF Investigators.
Qualitative Methodology in Cardiovascular Outcomes Research: A Contemporary Look
Review Article | By McIlvennan CK, Morris MA, Guetterman TC et al.
Qualitative and Mixed Methods Provide Unique Contributions to Outcomes Research
From Early Pharmacology to Recent Pharmacology Interventions in Acute Coronary Syndromes
Review Article | By Szummer K, Jernberg T, Wallentin L.
This focus seminar will take the reader through the history and pivotal trials that have formed the current state-of-the-art management for acute coronary syndromes. The identification of a ruptured plaque with thrombus formation and subsequent occlusion or downstream embolization in the coronary artery was the key to developing new and effective treatment strategies. The traditional wait-and-see approach with prolonged bedrest was repl...
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