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Management of Acute Myocardial Infarction During the COVID-19 Pandemic
CSC Expert Consensus on Principles of Clinical Management of Patients with Severe Emergent Cardiovascular Diseases during the COVID-19 Epidemic
ACC临床简报:新型冠状病毒对心脏的影响(2019-nCoV)
SCAI Expert Consensus Statement Update on Best Practices for Transradial Angiography and Intervention
AIM2-driven inflammasome activation in heart failure
Original Research | By K-P Kresoja, K-P Rommel, R Wachter et al.
AIMS - Recent evidence points towards a distinct obese phenotype among patients with heart failure with preserved ejection fraction (HFpEF). We aimed to identify differentially expressed circulating biomarkers in obese HFpEF patients and link them to disease severity and outcomes. METHODS AND RESULTS - From the LIFE-Heart study, 999 patients with HFpEF and 999 patients without h...
Original Research | By K Liu, B Song, MM Ning et al.
OBJECTIVES - The aim of this study was to investigate the effect of management on the risk for recurrent events among patients with cryptogenic ischemic stroke or transient ischemic attack. BACKGROUND - The combination of patent foramen ovale (PFO) and hypercoagulability may greatly increase the risk for paradoxical embolism. However, previous randomized controlled trials evaluating the efficacy of PF...
Multivessel PCI Guided by FFR or Angiography for Myocardial Infarction
Clinical Trial | By E Puymirat, G Cayla, for the FLOWER-MI Study Investigators et al.
BACKGROUND - In patients with ST-elevation myocardial infarction (STEMI) who have multivessel disease, percutaneous coronary intervention (PCI) for nonculprit lesions (complete revascularization) is superior to treatment of the culprit lesion alone. However, whether complete revascularization that is guided by fractional flow reserve (FFR) is superior to an angiography-guided procedure is unclear. METHODS&nb...
Original Research | By K Takahashi, PW Serruys, SYNTAX Extended Survival Study Investigators et al.
BACKGROUND - Ten-year all-cause death according to incomplete (IR) versus complete revascularization (CR) has not been fully investigated in patients with 3-vessel disease and left main coronary artery disease undergoing percutaneous coronary intervention (PCI) versus coronary artery bypass grafting (CABG). METHODS - The SYNTAX Extended Survival study (Synergy Between PCI With TAXUS and Ca...
Functional Mitral Regurgitation Outcome and Grading in Heart Failure With Reduced Ejection Fraction
Original Research | By G Benfari , C Antoine , B Essayagh et al.
OBJECTIVES - This study aims to define excess-mortality linked to functional mitral regurgitation (FMR) quantified in routine-practice. BACKGROUND - Appraisal of FMR in heart failure with reduced ejection fraction (HFrEF) is challenging because risks of excess mortality remain uncertain and guidelines diverge. METHODS - Cases of HFrEF (ejection-fraction <50%) Stage B-C th...
Clinical Trial | By N Curzen, Z Nicholas, FORECAST Investigators et al.
AIMS - Fractional flow reserve (FFRCT) using computed tomography coronary angiography (CTCA) determines both the presence of coronary artery disease and vessel-specific ischaemia. We tested whether an evaluation strategy based on FFRCT would improve economic and clinical outcomes compared with standard care. METHODS AND RESULTS - Overall, 1400 patients with stable chest pain in 11 centres we...
Clinical Trial | By D Collison, M Didagelos, M Aetesam-Ur-Rahman et al.
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