Defining a new standard for IVUS optimized drug eluting stent implantation: the PRAVIO study
Original Research | By Gerber RT, Latib A, Colombo A et al.
OBJECTIVES - Preliminary Investigation to the Angiographic Versus IVUS Optimization Trial is a single center prospective observational intravascular ultrasound (IVUS) guided stent implantation study assessing new criteria for optimal drug eluting stent (DES) deployment. BACKGROUND - IVUS assessment of DES often reveals underexpansion and malapposition. Optimal stent deployment is currentl...
Original Research | By Biondi-Zoccai G, Sheiban I, Romagnoli E et al.
BACKGROUND - Coronary bifurcations remain a challenging lesion subset for percutaneous coronary intervention (PCI). It is unclear whether intravascular ultrasound (IVUS) guidance can improve PCI results in bifurcations. We aimed to compare IVUS-guided PCI versus standard PCI in a large registry of patients undergoing PCI for bifurcations in the drug-eluting stent era. METHODS - A multicenter, retrospectiv...
Original Research | By Wakabayashi K, Lindsay J, Laynez-Carnicero A et al.
BACKGROUND - Percutaneous coronary intervention (PCI) of complex lesions (i.e., American College of Cardiology/American Heart Association class type C) remains challenging and the outcome may be compromised. The use of intravascular ultrasound (IVUS) to guide PCI was suggested to improve outcome. METHODS - A cohort of 1,984 patients who underwent PCI to type C lesions in...
Original Research | By Patel Y, Depta JP, Novak E et al.
Percutaneous coronary intervention (PCI) of bifurcation lesions remains challenging with a higher risk of adverse outcomes. Whether adjunctive intravascular ultrasound (IVUS) imaging improves outcomes of PCI of bifurcation lesions remains unclear. This study sought to determine the long-term clinical outcomes associated with using IVUS for percutaneous treatment of coronary bifurcation lesions. From April 2003 through ...
Original Research | By De la Torre Hernandez JM, Alfonso F, ESTROFA-LM Study Group.
Evidence regarding therapy with drug-eluting stents in the left main coronary artery (LM) is based mostly on trials performed with first-generation drug-eluting stents. The aim of this study was to evaluate long-term clinical outcomes after treatment for unprotected LM disease with paclitaxel-eluting stents (PES) and everolimus-eluting stents (EES). The ESTROFA-LM is a multicenter retrospective registry including...
The (R)Evolution of the CICU - Better for the Patient, Better for Education
Expert Opinion | By Valentin Fuster
“Revolutions are not push button affairs; rather, they evolve only if there exists a reservoir of hope and grievance that can be galvanized into popular action.” —Michael Parenti (1) As many of you know, I carefully scrutinize what are touted as the newest technological breakthroughs in medicine. However, one area of clinical care about which I feel quite excited is a more formal cardiovascular intensive care unit (CICU), be...
Original Research | By Yamamoto MH, Maehara A, Kim SS et al.
OBJECTIVES - We sought to assess plaque modification and stent expansion following orbital atherectomy (OA) for calcified lesions using optical coherence tomography (OCT). BACKGROUND - The efficacy of OA for treating calcified lesions is not well studied, especially using intravascular imaging in vivo. METHODS - OCT was performed preprocedure, post‐OA, and post‐stent ...
Original Research | By Usui E, Yonetsu T, Kakuta T et al.
OBJECTIVES - This study sought to investigate the relationship of unstable plaque features with physiological lesion severity and microvascular dysfunction. BACKGROUND - The functional severity of epicardial lesions and microvascular dysfunction are both related to adverse clinical outcomes. METHODS - We investigated 382 de novo intermediate and severe coronary lesions in 340 patients who...
Healthy Behavior, Risk Factor Control, and Survival in the COURAGE Trial
Original Research | By DJ Maron, GBJ Mancini, COURAGE Trial Group et al.
BACKGROUND - Individual risk factor control improves survival in patients with stable ischemic heart disease (SIHD). It is uncertain if multiple risk factor control further extends survival. Objectives This study determined whether a greater number of risk factors at goal predicted improved survival in SIHD patients. METHODS - Of 2,287 participants in the COURAGE (Clinical Outcomes Utiliz...