Guideline | By Roffi M, Patrono C, ESC Scientific Document Group.
Original Research | By Prejean SP, Din M, Reyes E et al.
In this Guidelines in Review, we review side-by-side the recommendations provided by the 2014 AHA/ACC Guideline for the management of patients with non-ST-elevation acute coronary syndromes and the 2015 ESC Guidelines for the management of acute coronary syndromes in patients presenting without persistent ST-segment elevation. We review the recommendations for imaging in the evaluation of patients with possible ACS f...
Management of Patients With NSTE-ACS: A Comparison of the Recent AHA/ACC and ESC Guidelines
Guideline | By Galiè N, Humbert M, ESC Scientific Document Group.
What's new in the Fourth Universal Definition of Myocardial infarction?
Economic and Quality-of-Life Outcomes of Natriuretic Peptide–Guided Therapy for Heart Failure
Original Research | By DB Mark, PA Cowper, KJ Anstrom et al.
BACKGROUND - The GUIDE-IT (GUIDing Evidence Based Therapy Using Biomarker Intensified Treatment in Heart Failure) trial prospectively compared the efficacy of an N-terminal pro–B-type natriuretic peptide (NT-proBNP)–guided heart failure treatment strategy (target NT-proBNP level <1,000 pg/ml) with optimal medical therapy alone in high-risk patients with heart failure and reduced ejection fraction. When ...
Economic and Quality-of-Life Outcomes of Natriuretic Peptide–Guided Therapy for Heart Failure
Original Research | By DB Mark, PA Cowper, KJ Anstrom et al.
BACKGROUND - The GUIDE-IT (GUIDing Evidence Based Therapy Using Biomarker Intensified Treatment in Heart Failure) trial prospectively compared the efficacy of an N-terminal pro–B-type natriuretic peptide (NT-proBNP)–guided heart failure treatment strategy (target NT-proBNP level <1,000 pg/ml) with optimal medical therapy alone in high-risk patients with heart failure and reduced ejection fraction. When ...
Natriuretic Peptide-Guided Heart Failure Therapy After the GUIDE-IT Study
Original Research | By Felker GM, Ahmad T, Anstrom KJ et al.
Review Article | By Ibrahim NE, Januzzi JL Jr.
PURPOSE OF REVIEW - Biomarker-guided management of patients with chronic heart failure with reduced ejection fraction (HFrEF) remains controversial. RECENT FINDINGS - Biomarkers have established roles for diagnosis and prognostication in HF. Pilot data suggested that use of natriuretic peptides might be helpful to guide HF care. The recent Guiding Evidence-Based Therapy Using Biomarker Intens...