Editorial | By W Sumaya, RF Storey.
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Review Article | By Maznyczka AM, Oldroyd KG, Berry C et al.
The goal of reperfusion therapies in ST-segment elevation myocardial infarction has evolved to include effective reperfusion of the microcirculation subtended by the culprit epicardial coronary artery. The index of microcirculatory resistance is measured using a pressure- and temperature-sensing coronary guidewire and quantifies microvascular dysfunction. The index of microcirculatory resistance is an independent predictor of microvascu...
Clinical Trial | By Henriques JP, Hoebers LP, EXPLORE Trial Investigators.
Review Article | By Iannaccone M, D'ascenzo F, Piazza F et al.
INTRODUCTION - The optimal management of patients with coronary chronic total occlusions (CTO) remains controversial. This meta-analysis aims to compare percutaneous coronary intervention of CTO (CTO-PCI) versus optimal medical therapy (OMT) in CTO patients. METHODS - A literature search with highly specific terms was conducted using MEDLINE, EMBASE, and Web of Science to identify m...
Original Research | By Ahn JH, Yang JH, Choi SH et al.
INTRODUCTION AND OBJECTIVES - Limited data are available on the clinical outcomes of optimal medical therapy (OMT) compared with revascularization by percutaneous coronary intervention (PCI) in patients with chronic total coronary occlusion (CTO) of the proximal or middle left anterior descending artery (pmLAD). Therefore, the objective of this study was to compare the long-term outcomes of patients with pmL...
Effects of Icosapent Ethyl on Total Ischemic Events: From REDUCE-IT
Original Research | By DL Bhatt, G Steg, and on behalf of the REDUCE-IT Investigators.
North American Expert Review of Rotational Atherectomy
Original Research | By Sharma SK, Tomey MI, Teirstein PS et al.
Rotational atherectomy (RA) is an established tool in interventional cardiology for treatment of calcified coronary lesions. Over 3 decades of clinical experience and research, techniques have matured and outcomes have improved. Heterogeneity exists, however, in RA utilization and technique. We assembled a group of experienced RA operators and device experts to summarize and critique key elements of contemporary RA technique...
Major trials in coronary intervention from 2018
Review Article | By Patel A, Marah N, Balan P et al.
PURPOSE OF REVIEW - This article will review the major clinical trials related to coronary intervention that were released in 2018. Areas of interest include lesion assessment, novel stent design, acute coronary syndromes (ACSs), and major breakthroughs in chronic total occlusion interventions. RECENT FINDINGS - The benefit of intracoronary imaging and hemodynamic assessment was demonstrated by...
Ticagrelor versus Clopidogrel in Patients with STEMI Treated with Fibrinolytic Therapy: TREAT Trial
Original Research | By Berwanger O, Lopes RD, Moia DDF et al.
BACKGROUND - The efficacy of ticagrelor in the long-term post ST-elevation myocardial infarction (STEMI) treated with fibrinolytic therapy remains uncertain. OBJECTIVES - To evaluate the efficacy of ticagrelor when compared with clopidogrel in STEMI patients treated with fibrinolytic therapy. METHODS - We conducted an international, multicenter, randomized, open-label ...