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Randomized study on simple versus complex stenting of coronary artery bifurcation lesions: the Nordic bifurcation study

Clinical Trial | By Steigen TK, M Maeng, the Nordic PCI Study Group et al.

Randomized study on simple versus complex stenting of coronary artery bifurcation lesions: the Nordic bifurcation study

Clinical Trial | By Steigen TK, M Maeng, the Nordic PCI Study Group et al.

Transcatheter Mitral Valve Replacement in Patients with Heart Failure and Secondary Mitral Regurgitation: From COAPT Trial

Clinical Trial | By FM Asch, PA Grayburn, the COAPT Investigators.

BACKGROUND- In the COAPT trial among patients with heart failure (HF) and moderate-to-severe (3+) or severe (4+) secondary mitral regurgitation (SMR), patients treated with the transcatheter mitral valve replacement (TMVR) had reduced rates of HF hospitalization and mortality compared with guideline-directed medical therapy (GDMT) alone.   OBJECTIVES- To describe the echocardiographic patient q...

Percutaneous Repair or Medical Treatment for Secondary Mitral Regurgitation: Outcomes at 2 years

Clinical Trial | By Iung B, Armoiry X, MITRA-FR Investigators.

Transcatheter versus Surgical Aortic Valve Replacement in Patients with Prior Cardiac Surgery in the Randomized PARTNER 2A Trial

Clinical Trial | By S Chen, B Redfors, MB Leon et al.

Three-Year Outcomes of the DKCRUSH-V Trial Comparing DK Crush With Provisional Stenting for Left Main Bifurcation Lesions

Clinical Trial | By X Chen, XB Li, the DKCRUSH-V Investigators.

Health Status after Transcatheter vs. Surgical Aortic Valve Replacement in Low-Risk Patients with Aortic Stenosis

Clinical Trial | By SJ Baron, EA Magnuson, the PARTNER 3 Investigators.

BACKGROUND - In patients with severe aortic stenosis (AS) at low surgical risk, treatment with transcatheter aortic valve replacement (TAVR) results in lower rates of death, stroke, and re-hospitalization at 1 year compared with surgical aortic valve replacement; however, the effect of treatment strategy on health status is unknown. OBJECTIVES - This study sought to compare health status outcomes of TAVR...

Effect of Intravascular Ultrasound-Guided Drug-Eluting Stent Implantation: Five-Year Follow-Up of the IVUS-XPL Randomized Trial

Clinical Trial | By SJ Hong, GS Mintz, the IVUS-XPL Investigators.

OBJECTIVES - The goal of this study was to evaluate whether the beneficial effect of use of intravascular ultrasound (IVUS) is sustained for long-term follow-up.   BACKGROUND - The use of IVUS promoted favorable 1-year clinical outcome in the IVUS-XPL trial. It is not known, however, whether this effect is sustained for long-term follow-up.   METHODS - The IVUS-XPL trial ...

Impact of Intravascular Ultrasound-Guided Drug-Eluting Stent Implantation on Patients With Chronic Kidney Disease: Subgroup Analysis From ULTIMATE Trial

Original Research | By JJ Zhang, XF Gao, the ULTIMATE Investigators.

BACKGROUND - Patients with chronic kidney disease (CKD) present more frequently with complex and extensive lesions, and intravascular ultrasound (IVUS)–guided drug-eluting stent (DES) implantation is associated with improved clinical outcomes in complex lesions. However, it still remains controversial that routine IVUS guidance could be beneficial to CKD patients. METHODS - This study aimed to ...

Five-Year Outcomes after PCI or CABG for Left Main Coronary Disease

Clinical Trial | By Stone GW, Kappetein AP, EXCEL Trial Investigators.

BACKGROUND - Long-term outcomes after percutaneous coronary intervention (PCI) with contemporary drug-eluting stents, as compared with coronary-artery bypass grafting (CABG), in patients with left main coronary artery disease are not clearly established. METHODS - We randomly assigned 1905 patients with left main coronary artery disease of low or intermediate anatomical complexity (according to assessment ...

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