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Contemporary Presentation and Management of Valvular Heart Disease: The EURObservational Research Programme Valvular Heart Disease II Survey

Original Research | By B Iung , V Delgado ,the EORP VHD II Investigators.

Chronic Kidney Disease and Coronary Artery Disease

Review Article | By MJ Sarnak, K Amann, S Bangalore et al.

Syncope After Percutaneous Coronary Intervention

Clinical Case Study | By Tsushima T, Sahadevan J, Intini A.

A man in his late 50s with a history of remote coronary artery bypass grafting presented with unstable angina and underwent percutaneous coronary intervention with a drug-eluting stent. He was discharged and prescribed ticagrelor, 90 mg twice daily, in addition to his home regimen of aspirin and metoprolol tartrate. Three months later, he experienced worsening exertional dyspnea and had multiple episodes of syncope. He had no history of syncopal...

Patient and Hospital Characteristics of Mitral Valve Surgery in the United States

Original Research | By Vemulapalli S, Grau-Sepulveda M, Habib R et al.

IMPORTANCE - Volume metrics may have relevance in the evaluation of valve center expertise. However, a paucity of data exists regarding the quantity, volume, and geographic location of mitral valve (MV) surgical centers in the United States and the proportion of underserved populations they treat. OBJECTIVES - To evaluate the hospital, patient, and procedural characteristics of mitral valve repair or replacement (MVRR) in...

Why and How to Measure Aortic Valve Calcification in Patients With Aortic Stenosis

Review Article | By T Pawade, T Sheth, E Guzzetti, MR Dweck et al.

The first-line evaluation of aortic stenosis severity is Doppler echocardiography. However, in up to 40% of patients, resting echocardiographic assessment of aortic stenosis severity is discordant, leading to clinical uncertainty. Interest has therefore grown in aortic valve calcium scoring by multidetector computed tomography (CT-AVC) as an alternative load independent assessment of aortic stenosis severity. This paper will briefly review the pathophys...

Transcatheter Interventions for Mitral Regurgitation: Multimodality Imaging for Patient Selection and Procedural Guidance

Original Research | By JJ Bax, P Debonnaire, P Lancellotti et al.

Transcatheter therapies to treat mitral regurgitation are rapidly developing. Currently, there are several devices commercially available to treat mitral regurgitation. The underlying cause of mitral regurgitation and specific anatomical aspects of the mitral valve and surrounding structures are considered when patients with symptomatic severe mitral regurgitation for transcatheter mitral valve therapies are selected. Multimodality imaging plays an impo...

Poor Long-Term Survival in Patients With Moderate Aortic Stenosis

Original Research | By G Strange, S Stewart, the National Echocardiography Database of Australia contributing sites

BACKGROUND - Historical data suggesting poor survival in patients with aortic stenosis (AS) who do not undergo treatment are largely confined to patients with severe AS.   OBJECTIVES - This study sought to determine the prognostic impact of all levels of native valvular AS.   METHODS - Severity of AS was characterized by convention and by statistical distribution in 122,809 male pa...

Ascending Aortic Length and Risk of Aortic Adverse Events: The Neglected Dimension

Original Research | By J Wu, MA Zafar, Yupeng Li, JA Elefteriades et al.

BACKGROUND - Little information is available regarding the longitudinal changes of the aneurysmal ascending aorta.   OBJECTIVES - This study sought to outline the natural history of ascending thoracic aortic aneurysm (ATAA) based on ascending aortic length (AAL) and develop novel predictive tools to better aid risk stratification.   METHODS - The ascending aortic diameters and lengths, a...

Thrombotic Versus Bleeding Risk After Transcatheter Aortic Valve Replacement: JACC Review Topic of the Week

Review Article | By A Mangieri, C Montalto, E Poletti et al.

A large amount of evidence supports the widespread use of transcatheter aortic valve replacement (TAVR) among patients who are at low to intermediate risk for surgery. However, several controversies exist about the optimal antithrombotic regimen to use in these patients. On the one hand, concerns about ischemic stroke, subclinical leaflet thrombosis, valve thrombosis, and long-term durability suggest the need for a stronger antithrombotic...

Efficacy and Safety of Ticagrelor Monotherapy in Patients Undergoing Multivessel PCI

Original Research | By K Takahashi, PW Serruys, P Chichareont et al.

BACKGROUND - Data on optimal antiplatelet treatment regimens in patients who undergo multivessel percutaneous coronary intervention (PCI) are sparse. OBJECTIVES - This post hoc study investigated the impact of an experimental strategy (1-month dual antiplatelet therapy [DAPT] followed by 23-month ticagrelor monotherapy) versus a reference regimen (12-month DAPT followed by 12-mon...

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Original Research 785
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Clinical Case Study 28
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Perspective 9
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2019 10

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JAMA Cardiol. 2
J Am Coll Cardiol. ACC Cardiovasc Imaging. 1
J Am Coll Cardiol. 2
J Am Coll Cardiol. 4
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