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Coronary Artery Plaque Characteristics Associated With Adverse Outcomes in the SCOT-HEART Study

| By MC Williams, AJ Moss, M Dweck et al.

BACKGROUND - Unlike most noninvasive imaging modalities, coronary computed tomography angiography can characterize subtypes of atherosclerotic plaque.   OBJECTIVES - The purpose of this study was to investigate the prognostic implications of adverse coronary plaque characteristics in patients with suspected coronary artery disease.   METHODS - In this SCOT-HEART (Sc...

Blood Pressure Assessment in Adults in Clinical Practice and Clinic-Based Research: JACC Scientific Expert Panel

| By P Muntner, PT Einhorn, 2017 National Heart, Lung, and Blood Institute Working Group.

The accurate measurement of blood pressure (BP) is essential for the diagnosis and management of hypertension. Restricted use of mercury devices, increased use of oscillometric devices, discrepancies between clinic and out-of-clinic BP, and concerns about measurement error with manual BP measurement techniques have resulted in uncertainty for clinicians and researchers. The National Heart, Lung, and Blood Institute of t...

Variation in Revascularization Practice and Outcomes in Asymptomatic Stable Ischemic Heart Disease

Clinical Trial | By A Czarnecki, F Qiu, G Elbaz-Greener et al.

OBJECTIVES - The aims of this study were to assess variation in revascularization of asymptomatic patients with stable ischemic heart disease, identify the predictors of variation, and determine if it was associated with clinical outcomes.   BACKGROUND - Management of stable ischemic heart disease in asymptomatic patients with obstructive coronary artery disease is controversial, potentially leading to pr...

Phenotypic Refinement of Heart Failure in a National Biobank Facilitates Genetic Discovery

Original Research | By Aragam KG, Chaffin M, GRADE Investigators.

Treatment of Drug-Eluting Stent In-Stent Restenosis With Drug-Eluting Balloons: A Systematic Review and Meta-Analysis

Review Article | By Liu S, Worme M, Bagai A et al.

OBJECTIVE - To evaluate the efficacy of drug-coated balloon (DEB) for the treatment of drug-eluting stent (DES) in-stent restenosis (ISR). METHODS - A comprehensive literature search was performed. The primary outcome was the composite of death, myocardial infarction (MI), and target-lesion revascularization (TLR) at longest available follow-up (range, 12-36 months). Outcomes for DEB ...

Long-term outcomes after treatment of bare-metal stent restenosis with paclitaxel-coated balloon catheters or everolimus-eluting stents: 3-year follow-up of the TIS clinical study

Original Research | By Pleva L, Kukla P, Zapletalova J et al.

BACKGROUND - The efficacy of paclitaxel-eluting balloon catheters (PEB) and drug-eluting stents for treatment of bare-metal stent restenosis (BMS-ISR) have been demonstrated in several studies with follow-up times of 9 to 12 months; however, the long-term outcomes of ISR treatment are less defined. OBJECTIVES - We aimed to compare the long-term efficacy of PEB and everolimus-eluting ste...

Treatment of Very Small De Novo Coronary Artery Disease With 2.0 mm Drug-Coated Balloons Showed 1-Year Clinical Outcome Comparable With 2.0 mm Drug-Eluting Stents

Original Research | By Sim HW, Ananthakrishna R, Loh JP et al.

OBJECTIVE - To evaluate the 1-year clinical outcomes of patients treated with 2.0 mm drug-coated balloon (DCB) vs 2.0 mm drug-eluting stent (DES) implantation in small-caliber vessel de novo coronary artery disease (CAD). METHODS - All patients treated with 2.0 mm DCB or 2.0 mm DES for very small vessel de novo CAD from July 2014 to June 2016 were included in this study. The primary ...

Comparison of new-generation drug-eluting stents versus drug-coated balloon for in-stent restenosis: a meta-analysis of randomised controlled trials

Review Article | By Cai JZ, Zhu YX, Wang XY et al.

Therapeutic efficacy of paclitaxel-coated balloon for de novo coronary lesions with diameters larger than 2.8 mm

Original Research | By Yu X, Ji FS, Xu F et al.

OBJECTIVE -  To evaluate the efficacy of paclitaxel-coated balloon for de novo coronary lesions with diameters ≥ 2.8 mm.   METHODS - This prospective study included 215 consecutive patients with 238 de novo lesions, who received paclitaxel-coated balloon angioplasty in Beijing Hospital from May 2014 to June 2016. According to the reference vessel diameter, the patients were divided into large ves...

Outcomes with drug-coated balloons in small-vessel coronary artery disease

Review Article | By Megaly M, Rofael M, Saad M et al.

BACKGROUND - Percutaneous coronary intervention (PCI) of small-vessel coronary artery disease (SVD) is associated with increased risk of restenosis. The use of drug-coated balloons (DCBs) in SVD has received limited study. OBJECTIVES - To assess the outcomes of DCB in the treatment of SVD compared with the standard of care. METHODS - We performed a meta-analysis of all stu...

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