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Dual Antiplatelet Therapy after PCI in Patients at High Bleeding Risk C-reactive protein and prognosis after percutaneous coronary intervention and bypass graft surgery for left main coronary artery disease: Analysis from the EXCEL trial Rotational Atherectomy in acute STEMI with heavily calcified culprit lesion is a rule breaking solution Parallel Murine and Human Plaque Proteomics Reveals Pathways of Plaque Rupture 2-Year Outcomes After Transcatheter Versus Surgical Aortic Valve Replacement in Low-Risk Patients Influence of Heart Rate on FFR Measurements: An Experimental and Clinical Validation Study Fractional flow reserve-guided PCI versus medical therapy in stable coronary disease Plaque Rupture, compared to Plaque Erosion, is associated with Higher Level of Pan-coronary Inflammation Clinical Outcomes and Cost-Effectiveness of Fractional Flow Reserve-Guided Percutaneous Coronary Intervention in Patients With Stable Coronary Artery Disease: Three-Year Follow-Up of the FAME 2 Trial (Fractional Flow Reserve Versus Angiography for Multivessel Evaluation) Evolving understanding of the heterogeneous natural history of individual coronary artery plaques and the role of local endothelial shear stress

LetterVolume 69, Issue 3, May 2017, Pages 407-410

JOURNAL:Indian Heart J. Article Link

Optical coherence tomography is a kid on the block: I would choose intravascular ultrasound

Dash D. Keywords: Percutaneous coronary intervention; Intravscular ultrasound; Optical coherence tomography; Vulnerable plaque; Biodegradable vascular scaffold

ABSTRACT

Intravascular imaging has improved our understanding of in vivo pathophysiology of coronary artery disease (CAD) and predicted decision-making in percutaneous coronary intervention (PCI). Intravascular ultrasound (IVUS) has emerged as the first clinical imaging method contributing significantly to modern PCI techniques. This modality has outlived many other intravascular techniques 26 years after its inception. It has assisted us in understanding dynamics of atherosclerosis and provides several unique insights into plaque burden, remodeling, and restenosis. It is useful as an imaging endpoint in large progression-regression trial and as workhorse in many catheterization laboratories. IVUS guidance appears to be most beneficial in complex lesion subsets that are being treated with drug-eluting stents. The recent introduction of optical coherence tomography (OCT), a light based imaging technique, has further expanded this field because of its higher resolution and faster image acquisition. The omnipresence of OCT raises the question: Does IVUS have a role in the era of OCT? Whether OCT is superior to IVUS in routine clinical practice? Even if OCT is currently gaining clinical significance in detailed planning of interventional strategies and stent optimization in complex lesion subsets, it is the much younger technique and has to prove its worth. Nevertheless, undoubtedly IVUS plays significant role in studies on coronary atherosclerosis and for guidance of PCI. In fact, both the methods are complementary rather than competitive.