Clinical Trial | By Givertz MM, Stevenson LW, CHAMPION Trial Investigators et al.
2016 ESC Guidelines for the diagnosis and treatment of acute and chronic heart failure
Guideline | By Ponikowski P, Voors AA, ESC Scientific Document Group. et al.
A Test in Context: E/A and E/e' to Assess Diastolic Dysfunction and LV Filling Pressure
Review Article | By Mitter SS, Shah SJ, Thomas JD.
Diastolic dysfunction represents a combination of impaired left ventricular (LV) relaxation, restoration forces, myocyte lengthening load, and atrial function, culminating in increased LV filling pressures. Current Doppler echocardiography guidelines recommend using early to late diastolic transmitral flow velocity (E/A) to assess diastolic function, and E to early diastolic mitral annular tissue velocity (E/e') to estimate LV filling pressu...
Clinical Trial | By Yannopoulos D, Bartos JA, Raveendran G et al.
BACKGROUND - The prevalence of coronary artery disease (CAD) among patients with refractory out-of-hospital(OH) ventricular fibrillation (VF)/ventricular tachycardia (VT) cardiac arrest is unknown. OBJECTIVES - The goal of this study was to describe the prevalence and complexity of CAD and report survival to hospital discharge in patients ...
Review Article | By Xu B, Tu S, Hu S et al.
BACKGROUND - Quantitative flow ratio (QFR) is a novel angiography-based method for deriving fractional flowreserve (FFR) without pressure wire or induction of hyperemia. The accuracy of QFR when assessed online in the catheterization laboratory has not been adequately examined to date. OBJECTIVES - The goal of this study was to assess the diagnosti...
Diagnostic accuracy of instantaneous wave free-ratio in clinical practice
Original Research | By Ding WY, Nair S, Appleby C.
AIMS - To evaluate the correlation between iFR and FFR in real-world clinical practice. METHODS AND RESULTS - Retrospective, single-centre study of 229 consecutive pressure-wire studies (np = 158). Real-time iFR and FFR measurements were performed for angiographically borderline stenoses. Functionally significant stenoses were defined as iFR <0.86 or FFR ≤...
Review Article | By Jang JS, Song YJ, Kang W et al.
OBJECTIVES - The aim of this study was to systematically review and perform a meta-analysis of randomized trials and observational studies of intravascular ultrasound (IVUS)-guided versus angiography-guided implantation of drug-eluting stents (DES). BACKGROUND - Although studies in the bare-metal stents era suggested that there were clinical benefits to IVUS guidance, it is still controversial whethe...
Silent Myocardial Infarction and Long-Term Risk of Heart Failure: The ARIC Study
Original Research | By Qureshi WT, Zhang ZM, Soliman EZ et al.
BACKGROUND - Although silent myocardial infarction (SMI) accounts for about one-half of the total number of myocardial infarctions (MIs), the risk of heart failure (HF) among patients with SMI is not well established. OBJECTIVES - The purpose of this study was to examine the association of SMI and clinically manifested myocardial infarction (CMI) with HF, as compared with patients with no MI....
Clinical Trial | By Motovska Z, Hlinomaz O, PRAGUE-18 Study Group et al.
BACKGROUND - Early outcomes of patients in the PRAGUE-18 (Comparison of Prasugrel and Ticagrelor in the Treatment of Acute Myocardial Infarction) study did not find any significant differences between 2 potent P2Y12 inhibitors. OBJECTIVES - The 1-year follow-up of the PRAGUE-18 study focused on: 1) a comparison of efficacy and safety between prasugrel and ticagrelor; and 2) the risk of ma...