2023 ESC Guidelines for the management of acute coronary syndromes
Guideline | By RA Byrne, B Ibanez, ESC Scientific Document Group.
Definition, classification and diagnosis of pulmonary hypertension
Original Research | By EM Handberg, CNB Merz, RM Cooper-Dehoff et al.
BACKGROUND - Approximately half of all women with anginal symptoms and/or signs of ischemia and no obstructive coronary artery disease (INOCA) referred for coronary angiography have elevated risk for major adverse cardiac events (MACE), poor quality of life and resource consumption. Yet, guidelines focus on symptom management while clinical practice typically advocates only reassurance. Pilot studies of INOCA subjects s...
Original Research | By D Kinoshita, K Suzuki, IK Jang et al.
Vulnerable or High-Risk Plaque: A JACC: Cardiovascular Imaging Position Statement
Recommandation Statement | By R Vergallo, SJ Park, IK Jang et al.
The concept of high-risk plaque emerged from pathologic and epidemiologic studies 3 decades ago that demonstrated plaque rupture with thrombosis as the predominant mechanism of acute coronary syndrome and sudden cardiac death. Thin-cap fibroatheroma, a plaque with a large lipidic core covered by a thin fibrous cap, is the prototype of the rupture-prone plaque and has been traditionally defined as “vulnerable plaque.” Although knowledge on th...
Clinical Trial | By JM Liu, Y Li; ESPRIT Collaborative Group.
BACKGROUND - Uncertainty exists about whether lowering systolic blood pressure to less than 120 mm Hg is superior to that of less than 140 mm Hg, particularly in patients with diabetes and patients with previous stroke. METHODS - In this open-label, blinded-outcome, randomised controlled trial, participants with high cardiovascular risk were enrolled from 116 hospitals or communities in China. We...
Clinical Trial | By XB Li, Z Ge; IVUS-ACS Investigators.
BACKGROUND - Intravascular ultrasound-guided percutaneous coronary intervention has been shown to result in superior clinical outcomes compared with angiography-guided percutaneous coronary intervention. However, insufficient data are available concerning the advantages of intravascular ultrasound guidance for patients with an acute coronary syndrome. This trial aimed to investigate whether the use of intravascular ultrasound guidanc...
Clinical Trial | By J Wen, S Dohad, R Shlofmitz et al.
BACKGROUD - Treatment of small vessel (SV) coronary artery disease is associated with higher restenosis rates. Drug-coated balloons offer a promising treatment option for stent failure by delivering an antiproliferative drug and avoiding an additional metal implant. However, evidence supporting the use of paclitaxel-coated balloons (PCBs) for in-stent restenosis (ISR) in SVs is limited. OBJECTIV...