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Extended antiplatelet therapy with clopidogrel alone versus clopidogrel plus aspirin after completion of 9- to 12-month dual antiplatelet therapy for acute coronary syndrome patients with both high bleeding and ischemic risk. Rationale and design of the OPT-BIRISK double-blinded, placebo-controlled randomized trial Effect of the PCSK9 Inhibitor Evolocumab on Total Cardiovascular Events in Patients With Cardiovascular DiseaseA Prespecified Analysis From the FOURIER Trial Revascularization in Patients With Left Main Coronary Artery Disease and Left Ventricular Dysfunction Long-Term Outcomes After PCI or CABG for Left Main Coronary Artery Disease According to Lesion Location Comparison of Early Surgical or Transcatheter Aortic Valve Replacement Versus Conservative Management in Low-Flow, Low-Gradient Aortic Stenosis Using Inverse Probability of Treatment Weighting: Results From the TOPAS Prospective Observational Cohort Study Transcatheter Versus Surgical Aortic Valve Replacement in Low-Risk Patients Transcatheter Aortic Valve Replacement in Low-Risk Patients With Symptomatic Severe Bicuspid Aortic Valve Stenosis Right ventricular function and outcome in patients undergoing transcatheter aortic valve replacement 5-Year Outcomes After TAVR With Balloon-Expandable Versus Self-Expanding Valves: Results From the CHOICE Randomized Clinical Trial Stroke Rates Following Surgical Versus Percutaneous Coronary Revascularization

Guidelinehttps://academic.oup.com/eurheartj/advance-article/doi/10.1093/eurheartj/ehaa575/5898842

JOURNAL:Eur Heart J. Article Link

2020 ESC Guidelines for the management of acute coronary syndromes in patients presenting without persistent ST-segment elevation: The Task Force for the management of acute coronary syndromes in patients presenting without persistent ST-segment elevation of the European Society of Cardiology (ESC)

J-P Collet, H Thiele, E Barbato et al. Keywords: ACS without persistent ST-segment elevation; Guidelines; acute cardiac care; angioplasty; anticoagulation; antiplatelet; apixaban; aspirin; atherothrombosis; betablockers; bleedings; bivalirudin; CABG; cangrelor; chest pain unit; clopidogrel; dabigatran; diabetes; DAPT; early invasive strategy; edoxaban; enoxaparin; fondaparinux; glycoprotein IIb/IIIa inhibitors; heparin; high-sensitivity troponin; MINOCA; myocardial ischaemia; MI; nitrates; platelet inhibition; prasugrel; revascularization; rhythm monitoring; rivaroxaban; stent; ticagrelor; triple therapy; unstable angina

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