Clinical Trial | By G Giustino, PW Serruys, GW Stone et al.
OBJECTIVES - The aim of this study was to investigate the incidence and impact on mortality of repeat revascularization after index percutaneous coronary intervention (PCI) or coronary artery bypass grafting (CABG) for left main coronary artery disease (LMCAD). BACKGROUND - The impact on mortality of the need of repeat revascularization following PCI or CABG in patients with unprotected LMCAD is ...
Management of Asymptomatic Severe Aortic Stenosis: Evolving Concepts in Timing of Valve Replacement
Review Article | By BR Lindman, MR Dweck, P Lancellotti et al.
New insights into the pathophysiology and natural history of patients with aortic stenosis, coupled with advances in diagnostic imaging and the dramatic evolution of transcatheter aortic valve replacement, are fueling intense interest in the management of asymptomatic patients with severe aortic stenosis. An intervention that is less invasive than surgery could conceivably justify pre-emptive transcatheter aortic valve replacement in subsets of patients, rat...
Five-Year Outcomes of Transcatheter or Surgical Aortic-Valve Replacement
Clinical Trial | By RR Makkar, VH Thourani, the PARTNER 2 Investigators.
BACKGROUND - There are scant data on long-term clinical outcomes and bioprosthetic-valve function after transcatheter aortic-valve replacement (TAVR) as compared with surgical aortic-valve replacement in patients with severe aortic stenosis and intermediate surgical risk. METHODS - We enrolled 2032 intermediate-risk patients with severe, symptomatic aortic stenosis at 57 centers. Patients were st...
Original Research | By Beohar N, Kaltenbach LA, Wojdyla D et al.
BACKGROUND - Adjunctive coronary atherectomy (CA) can be utilized in treating severely calcified coronary lesions; however, the temporal trends, patient selection, and variation in use of CA have not been well described. We sought to assess the trends in usage, interhospital variability, and outcomes with CA among patients undergoing percutaneous coronary intervention (PCI). METHODS - All patients undergoing P...
Review Article | By GWM Wijntjens , EL van Uffelen, TP van de Hoef et al.
BACKGROUND - Intravenous infusion of adenosine is considered standard practice for fractional flow reserve (FFR) assessment but is associated with adverse side-effects and is time-consuming. Intracoronary bolus injection of adenosine is better tolerated by patients, cheaper, and less time-consuming. However, current literature remains fragmented and modestly sized regarding the equivalence of intracoronary versus intravenous adenosin...
Routine Continuous Electrocardiographic Monitoring Following Percutaneous Coronary Interventions
Original Research | By MA Al-Hijji , R Gulati,M Singh et al.
BACKGROUND - The clinical utility of routine electrocardiographic monitoring following percutaneous coronary interventions (PCI) is not well studied. METHODS - We prospectively evaluated the incidence, cost, and the clinical implications of actionable arrhythmia alarms on telemetry monitoring following PCI. One thousand three hundred fifty-eight PCI procedures (989 [72.8%] for acute coronary syndr...
ACC临床简报:新型冠状病毒对心脏的影响(2019-nCoV)
Original Research | By Satoru Suzuki , K Kaikita, E Yamamoto et al.
Original Research | By G Witberg, BD Bruyne, WF Fearon et al.
OBJECTIVES - This study sought to assess the diagnostic performance of FFRangio (CathWorks, Kfar Saba, Israel), an angiogram-derived fractional flow reserve (FFR) technology. BACKGROUND - Despite practice guidelines recommendations, the use of coronary physiologic assessment in daily practice remains low for patients undergoing coronary angiography. Angiogram-derived FFR technologies have ...
Original Research | By AR van Rosendael, AM Bax, JM Smit et al.
AIMS - In patients without obstructive coronary artery disease (CAD), we examined the prognostic value of risk factors and atherosclerotic extent. METHODS AND RESULTS - Patients from the long-term CONFIRM registry without prior CAD and without obstructive (≥50%) stenosis were included. Within the groups of normal coronary computed tomography angiography (CCTA) (N = 1849) and non-ob...