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荐读文献
Management of Acute Myocardial Infarction During the COVID-19 Pandemic
CSC Expert Consensus on Principles of Clinical Management of Patients with Severe Emergent Cardiovascular Diseases during the COVID-19 Epidemic
ACC临床简报:新型冠状病毒对心脏的影响(2019-nCoV)
SCAI Expert Consensus Statement Update on Best Practices for Transradial Angiography and Intervention
Outcomes of TTVI in Patients With Pacemaker or Defibrillator Leads: Data From the TriValve Registry
Original Research | By M Taramasso, M Gavazzoni, A Pozzoli et al.
OBJECTIVES - The interference of a transtricuspid cardiac implantable electronic device (CIED) lead with tricuspid valve function may contribute to the mechanism of tricuspid regurgitation (TR) and poses specific therapeutic challenges during transcatheter tricuspid valve intervention (TTVI). Feasibility and efficacy of TTVI in presence of a CIED is unclear. BACKGROUND - Feasibility of TTVI in pres...
Original Research | By BM Scirica, BA Bergmark, DA Morrow et al.
BACKGROUND - Recent emphasis on reduced duration and/or intensity of antiplatelet therapy following percutaneous coronary intervention (PCI) irrespective of indication for PCI may fail to account for the substantial risk of subsequent nontarget lesion events in acute coronary syndrome (ACS) patients. OBJECTIVES - The authors sought to examine the effect of more potent antiplatelet therapy on the basis of the ti...
Clinical Trial | By SP Marso, FMM Baeres, and on behalf of the LEADER Trial Investigators.
BACKGROUND - More data regarding effects of glucagon-like peptide-1 receptor agonists in patients with type 2 diabetes (T2D) and heart failure (HF) are required. OBJECTIVES - The purpose of this study was to investigate the effects of liraglutide on cardiovascular events and mortality in LEADER (Liraglutide Effect and Action in Diabetes: Evaluation of Cardiovascular Outcome Results) p...
Original Research | By Y Fan, XJ Guo, LS Wang et al.
BACKGROUND - In mammalian, regenerative therapy after myocardial infarction (MI) is hampered by the limited regenerative capacity of adult heart, while a transient regenerative capacity is maintained in the neonatal heart. Systemic phosphorylation signaling analysis on ischemic neonatal myocardium might be helpful to identify key pathways involved in heart regeneration. We aimed to define kinase-substrate network in ischem...
Diuretic Therapy for Patients With Heart Failure JACC State-of-the-Art Review
Review Article | By GM Felker, DH Ellison, W Mullens et al.
Expansion of extracellular fluid volume is central to the pathophysiology of heart failure. Increased extracellular fluid leads to elevated intracardiac filling pressures, resulting in a constellation of signs and symptoms of heart failure referred to as congestion. Loop diuretics are one of the cornerstones of treatments for heart failure, but in contrast to other therapies, robust clinical trial evidence to guide the use of diuretics is sparse. A nuanc...
Early Diagnosis of Myocardial Infarction With Point-of-Care High-Sensitivity Cardiac Troponin I
Original Research | By J Boeddinghaus, T Nestelberger, and for the APACE Investigators et al.
Clinical Trial | By F Leclercq, P Robert, M Akodad et al.
OBJECTIVES - The aim of this study was to evaluate device success of transcatheter aortic valve replacement (TAVR) using new-generation balloon-expandable prostheses with or without balloon aortic valvuloplasty (BAV). BACKGROUND - Randomized studies are lacking comparing TAVR without BAV against the conventional technique of TAVR with BAV. METHO...
Original Research | By A Kawsara, F Alqahtani, MF Eleid et al.
OBJECTIVES - This study sought to use a national representative database to assess the incidence, predictors, and outcomes of balloon aortic valvuloplasty (BAV) as a bridge to transcatheter aortic valve replacement (TAVR) in contemporary practice. BACKGROUND - Nationwide data on the use and outcomes of BAV as a bridge to TAVR are limited. METHODS -...
Original Research | By DJ Angiolillo, D Capodanno, N Danchin et al.
OBJECTIVES - The aim of this study was to develop a risk score integrating cytochrome P450 2C19 loss-of-function genotypes with clinical risk factors influencing clopidogrel response that would allow the identification with more precision of subjects at risk for high platelet reactivity (HPR) and adverse clinical outcomes. BACKGROUND - Clopidogrel is the most broadly used platelet P2Y12 inhibitor. Ho...
Intravascular Ultrasound to Guide Left Main Stem Intervention: A Sub-Study of the NOBLE Trial
Original Research | By A Ladwiniec, SJ Walsh, EH Christiansen et al.
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