Factors associated with pulmonary arterial hypertension (PAH) in systemic sclerosis (SSc)
Review Article | By YX Jiang, MA Turk, JE Pope et al.
BACKGROUND - Pulmonary arterial hypertension (PAH) in systemic sclerosis (SSc) is a lethal complication affecting 8–15% of patients. Screening tests such as echocardiography and pulmonary function tests allow for triaging patients for diagnosis by right heart catheterization. Understanding risk factors of SSc-PAH could help differentiate high-risk patients. METHODS - A systematic re...
Original Research | By XB Li, J Kan, SS Chen et al.
BACKGROUND - Provisional side branch (SB) stenting is correlated with target vessel myocardial infarction (TVMI) in patients with coronary bifurcation lesions. However, the mechanisms underlying this association remain unknown. OBJECTIVES - To determine the correlation between SB lesion length with vulnerable plaques and TVMI using optical coherence tomography (OCT). BAC...
Management of Myocardial Revascularization Failure: An Expert Consensus Document of the EAPCI
Modifiable lifestyle factors and heart failure: A Mendelian randomization study
Clinical Trial | By S van Oort, JWJ Beulens, AJ van Ballegooijen et al.
Original Research | By JA Borovac, D Glavas, ZS Grabovac et al.
The prognostic role of mid-range ejection fraction in ST-segment elevation myocardial infarction
Original Research | By M Alkhalil, A Kearney, D MacElhatton et al.
OBJECIVE - There is a paucity of studies investigating the impact of mid-range ejection fraction (mrEF) on clinical outcomes, including ventricular arrhythmias, in ST-segment-elevation myocardial infarction (STEMI). We sought to investigate the prognostic role of mrEF post STEMI and whether recommended medical therapy may modify future risk. METHODS - 533 consecutive patients from a single lar...
Original Research | By M Verdoiaab, M Nardinb, R Gioscia et al.
BACKGROUND - Neutrophil to lymphocyte ratio (NLR) has emerged as a useful and easy-to-assess prognostic tool and biomarker of cardiovascular risk. However, few studies have evaluated its role on platelet inhibition among patients on dual antiplatelet therapy (DAPT), and especially in the settings of acute coronary syndromes (ACS). We aimed at assessing the impact of NLR on platelet reactivity and the risk of major ischemic...
Review Article | By G Marquis-Gravel, DJ Moliterno, SG Goodman et al.
The role of percutaneous coronary interventions in addition to medical therapy for patients with stable coronary artery disease continues to be debated in routine clinical practice, despite more than 2 decades of randomized controlled trials. The residual uncertainty arises from particular challenges facing revascularization trials. Which endpoint do doctors care about, and which do patients care about? Which participants should be enrolled? What bac...