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荐读文献
Management of Acute Myocardial Infarction During the COVID-19 Pandemic
CSC Expert Consensus on Principles of Clinical Management of Patients with Severe Emergent Cardiovascular Diseases during the COVID-19 Epidemic
ACC临床简报:新型冠状病毒对心脏的影响(2019-nCoV)
SCAI Expert Consensus Statement Update on Best Practices for Transradial Angiography and Intervention
Cardiovascular Toxicity in Cancer Survivors: Current Guidelines and Future Directions
Expert Opinion | By Carlyn Tan, MD; Crystal Denlinger, MD
Introduction - An individual is defined by the National Cancer Institute as a survivor "from the time of diagnosis through the balance of his or her life."1 Due to improved diagnosis and treatment, the number of cancer survivors in the United States reached nearly 15.5 million currently.2,3 More than 60% and 40% of cancer survivors are alive 5 and ≥10 years after diagnosis, respectively, contributing to a growing population of aging survivors at risk for l...
Clinical Trial | By AH Gershlick, DE Kandzari, GW Stone et al.
OBJECTIVES - The authors sought to determine the extent to which the site of the left main coronary artery (LM) lesion (distal bifurcation versus ostial/shaft) influences the outcomes of revascularization with percutaneous coronary intervention (PCI) versus coronary artery bypass grafting (CABG). BACKGOURND - Among 1,905 patients with LM disease and site-assessed SYNTAX scores of <32 randomized in ...
Long-Term Clinical Outcomes and Optimal Stent Strategy in Left Main Coronary Bifurcation Stenting
Clinical Trial | By S Cho, TS Kang, J-S Kim et al.
OBJECTIVES - This study sought to investigate the long-term clinical effects of stent generation and stent strategy for left main coronary artery (LMCA) bifurcation lesion treatment. BACKGROUD - Limited data are available to assess long-term clinical outcomes after stenting, including use of current-generation drug-eluting stent (C-DES) for treatment of LMCA bifurcation lesions. METHODS ...
Complex PCI procedures: challenges for the interventional cardiologist
Review Article | By Werner N, Nickenig G, Sinning JM.
In recent years, the percentage of patients with multivessel disease and multiple complex stenoses have significantly increased. One factor contributing to this increase is the proportion of elderly and very elderly patients who have been turned down by the Heart Team for surgical revascularization (Landes et al. in Catheter Cardiovasc Interv, https://doi.org/10.1002/ccd.27375 , 2017; Waldo et al. in Circulation 130:2295-2301, https://doi.org/10.116...
Original Research | By Waldo SW, Secemsky EA, Yeh RW et al.
BACKGROUND - Decisions to proceed with surgical versus percutaneous revascularization for multivessel coronary artery disease are often based on subtle clinical information that may not be captured in contemporary registries. The present study sought to evaluate the association between surgical ineligibility documented in the medical record and long-term mortality among patients with unprotected left main or multivessel coronary art...
Original Research | By Landes U, Bental T, Levi A et al.
BACKGROUND - The last decade, regarded as the DES era in PCI, has witnessed significant advances in the management of coronary disease. We aimed to assess temporal trends in the practice and outcome of percutaneous coronary intervention (PCI) during the drug eluting stent (DES) era. METHODS - We analyzed 18,641 consecutive PCI's performed between January 2004 and December 2016, distinguished by procedural d...
Original Research | By Mohr FW, Morice MC, Kappetein AP et al.
BACKGROUND - We report the 5-year results of the SYNTAX trial, which compared coronary artery bypass graft surgery (CABG) with percutaneous coronary intervention (PCI) for the treatment of patients with left main coronary disease or three-vessel disease, to confirm findings at 1 and 3 years. METHODS - The randomised, clinical SYNTAX trial with nested registries took place in 85 centres in the USA an...
Clinical Trial | By Tonino PA, Fearon WF, De Bruyne B et al.
OBJECTIVES - The purpose of this study was to investigate the relationship between angiographic and functional severity of coronary artery stenoses in the FAME (Fractional Flow Reserve Versus Angiography in Multivessel Evaluation) study. BACKGROUND - It can be difficult to determine on the coronary angiogram which lesions cause ischemia. Revascularization of coronary stenoses that induce ischemia improv...
Original Research | By Behan MW, Holm NR, de Belder AJ et al.
AIMS - Randomized trials of coronary bifurcation stenting have shown better outcomes from a simple (provisional) strategy rather than a complex (planned two-stent) strategy in terms of short-term efficacy and safety. Here, we report the 5-year all-cause mortality based on pooled patient-level data from two large bifurcation coronary stenting trials with similar methodology: the Nordic Bifurcation Study (NORDIC I) and the British...
Blood CSF1 and CXCL12 as Causal Mediators of Coronary Artery Disease
Original Research | By J Sjaarda, H Gerstein, M Chong et al.
BACKGROUND - Identification of biomarkers that cause coronary artery disease (CAD) has led to important advances in prevention and treatment. Epidemiological analyses have identified many biomarker-CAD relationships; however, these associations may arise from reverse causation and/or confounding and therefore may not represent true causal associations. Mendelian randomization (MR) analyses overcome these limitations. ...
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