Prevalence of potential drug-drug interactions in cancer patients treated with oral anticancer drugs
Original Research | By van Leeuwen RW, Brundel DH, Neef C et al.
Original Research | By Watanabe M, Okura H, Okamura A et al.
OBJECTIVES - The aim is to investigate the usefulness of longitudinal reconstructed optical coherence tomography (OCT) images in selecting the reverse wire (RW) technique for inserting a guidewire into a side branch (SB). BACKGROUND - It is sometimes necessary to protect the SB with a guidewire to prevent SB complications in PCI for bifurcation lesions. The RW is a novel method for guidewir...
Original Research | By Nomura T, Kikai M, Hori Y et al.
In practical settings of percutaneous coronary intervention (PCI), we sometimes encounter difficulty in introducing a guidewire (GW) to the markedly angulated side branch (SB), and the reverse wire technique is considered as a last resort to overcome such a situation. We analyzed 12 cases that underwent PCI with dual-lumen microcatheter-facilitated reverse wire technique between January 2013 and July 2016. We retrospectively...
Alirocumab Reduces Total Nonfatal Cardiovascular and Fatal Events in the ODYSSEY OUTCOMES Trial
Clinical Trial | By M Szarek, HD White, PH Steg, ODYSSEY OUTCOMES Committees and Investigators.
Effect of Aspirin on All-Cause Mortality in the Healthy Elderly
Clinical Trial | By McNeil JJ, Nelson MR, ASPREE Investigator Group.
BACKGROUND - In the primary analysis of the Aspirin in Reducing Events in the Elderly (ASPREE) trial, now published in the Journal, we report that the daily use of aspirin did not provide a benefit with regard to the primary end point of disability-free survival among older adults. A numerically higher rate of the secondary end point of death from any cause was observed with aspirin than with placebo. METHOD...
Longitudinal Change in Galectin-3 and Incident Cardiovascular Outcomes
Original Research | By A Ghorbani, V Bhambhani, RH Christenson et al.
BACKGROUND - Galectin-3 (Gal-3) has been associated with heart failure (HF) and poor cardiovascular outcomes. However, the effect of longitudinal changes in Gal-3 on clinical outcomes remains unclear. OBJECTIVES - The authors sought to study clinical determinants of change in Gal-3 among community-dwelling individuals. Further, they sought to examine the role of serial Gal-3 measurements in ...
Guideline | By 中华医学会心血管病学分会肺血管病学组, 中华心血管病杂志编辑委员会。
2007年7月中华医学会心血管病学分会、中华心血管病杂志编辑委员会联合发布了我国"肺动脉高压筛查诊断与治疗专家共识",该共识参考2003年在意大利威尼斯举办的第3次世界肺高血压大会对肺高血压的定义、临床分类、诊断流程和治疗策略,基于当时国际上临床实践的现状,并结合我国实际情况,对我国肺动脉高压(pulmonary arterial hypertension,PAH)的筛查、诊断与治疗均提出了切实可行的建议,对规范临床医生的诊疗行为、提高我国肺高血压临床诊治水平发挥了重要作用。
Original Research | By Huang X, Redfors B, Stone GW et al.
OBJECTIVES - Percutaneous coronary intervention (PCI) is often favoured over coronary artery bypass grafting (CABG) surgery for revascularization in patients with chronic obstructive pulmonary disease (COPD). We studied whether COPD affected clinical outcomes according to revascularization in the Evaluation of XIENCE Versus Coronary Artery Bypass Surgery for Effectiveness of Left Main Revascularization (EXCEL) trial...
Original Research | By Siasos G, Tsigkou V, Stone PH et al.
PURPOSE OF REVIEW - The natural history of coronary atherosclerosis is complex and atherosclerotic plaques exhibit large morphologic and functional variability within the same individual as well as over time. The purpose of this article is to review the role of blood flow patterns and shear stress on the development of microvascular and epicardial endothelial dysfunction and atherosclerosis progression. RECEN...