Original Research | By Funatsu A, Kobayashi T, Mizobuchi M et al.
The mechanism of how angiographic results following paclitaxel-coated balloon (PCB) treatment for small vessel disease affect patient outcome remains unknown. In the present study, we aimed to investigate the correlation between coronary dissection immediately after PCB angioplasty and midterm outcome. From March 2014 to March 2017, 171 consecutive patients with 228 native coronary artery lesions who received PCB ang...
Original Research | By Miura K, Tada T, Habara S et al.
BACKGROUND - Little is known of the relationship between optical coherence tomography (OCT) findings and recurrent restenosis after paclitaxel-coated balloon (PCB) angioplasty for drug-eluting stent in-stent restenosis (DES-ISR). To identify the predictors of recurrent restenosis after PCB angioplasty, we investigated quantitative and qualitative OCT findings during PCB angioplasty for DES-ISR. Methods and Results: In al...
Clinical Trial | By Baystrukov V, Kretov EI, Boukhris M et al.
BACKGROUND - The optimal strategy to treat bifurcation lesions (BFLs) in a percutaneous coronary intervention (PCI) for chronic total occlusions (CTOs) remains unknown. AIMS - We sought to assess whether T-provisional or mini-crush is appropriate for BFLs within CTO vessels. PATIENTS AND METHODS - From January 2011 to December 2013, patients who underwent successful CTO gu...
Original Research | By Baeza Garzón F, Pan Álvarez-Ossorio M, Romero Moreno MÁ et al.
| By A Masri, AM Altibi, S Erqou et al.
OBJECTIVES - This study sought to synthesize the available evidence on the use of the wearable cardioverter-defibrillator (WCD). BACKGROUND - Observational WCD studies for the prevention of sudden cardiac death have provided conflicting data. The VEST (Vest Prevention of Early Sudden Death) trial was the first randomized controlled trial (RCT) showing no reduction in sudden cardiac death as compared to ...
Wearable Cardioverter-Defibrillator after Myocardial Infarction
Clinical Trial | By Olgin JE, Pletcher MJ, VEST Investigators et al.
BACKGROUND - Despite the high rate of sudden death after myocardial infarction among patients with a low ejection fraction, implantable cardioverter-defibrillators are contraindicated until 40 to 90 days after myocardial infarction. Whether a wearable cardioverter-defibrillator would reduce the incidence of sudden death during this high-risk period is unclear. METHODS - We randomly assigned (in a 2:1 ratio) patients w...
Original Research | By DeFina LF, Radford NB, Barlow CE et al.
IMPORTANCE - Few data are available to guide clinical recommendations for individuals with high levels of physical activity in the presence of clinically significant coronary artery calcification (CAC). OBJECTIVE - To assess the association among high levels of physical activity, prevalent CAC, and subsequent mortality risk. DESIGN, SETTING, AND PARTICIPANTS ...
Heart Disease and Stroke Statistics-2019 Update: A Report From the American Heart Association
Expert Opinion | By Karlee K Hoffman, MD; Sir Raymond L. Benza, MD, FACC; Manreet Kanwar, MBBS, FACC
Pulmonary arterial hypertension (PAH) is a chronic disease of the pulmonary vasculature characterized by progressive narrowing of the pulmonary arteries, which in turn leads to increased pulmonary vascular resistance, right heart failure, and death.1 There has been a significant improvement in the available medical therapeutic options in this field that have impacted the short-term survival and morbidity in these patients.2 However, the medi...