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Clinical Characteristics and Outcomes of STEMI Patients With Cardiogenic Shock and Cardiac Arrest

Original Research | By MA Omer, JM Tyler, TD Henry et al.

OBJECTIVES - This study sought to compare the clinical characteristics and long-term outcomes of patients with ST-segment elevation myocardial infarction (STEMI) with and without cardiogenic shock (CS) or cardiac arrest (CA) before percutaneous coronary intervention (PCI).   BACKGROUND - Patients with STEMI complicated by CS or CA are underrepresented in STEMI registries. &nbs...

Percutaneous Atriotomy for Levoatrial–to–Coronary Sinus Shunting in Symptomatic Heart Failure: First-in-Human Experience

Clinical Case Study | By T Simard, M Labinaz, F Zahr et al.

Sex-Based Outcomes in Patients With a High Bleeding Risk After Percutaneous Coronary Intervention and 1-Month Dual Antiplatelet Therapy: A Secondary Analysis of the LEADERS FREE Randomized Clinical Trial

Clinical Trial | By R Mehran, J Chandrasekhar, P Urban et al.

IMPORTANCE - Female sex has been identified as a risk factor for bleeding after percutaneous coronary intervention (PCI) and may have contributed to the underuse of drug-eluting stents in women. This risk may be further enhanced among patients with a high bleeding risk. OBJECTIVE - To assess the 2-year outcomes by sex in patients with a high bleeding risk who were enrolled in the LEADERS FREE trial...

Drug-Coated Balloons for Coronary Artery Disease: Third Report of the International DCB Consensus Group

Consensus | By RV Jeger, S Eccleshall et al for the International DCB Consensus Group

Lipoprotein(a) in Alzheimer, Atherosclerotic, Cerebrovascular, Thrombotic, and Valvular Disease: Mendelian Randomization Investigation

Letter | By SC Larsson, D Gill , AM Mason et al.

Bayesian Interpretation of the EXCEL Trial and Other Randomized Clinical Trials of Left Main Coronary Artery Revascularization

Original Research | By JM Brophy.

IMPORTANCE - Patients with left main coronary artery disease have improved outcomes with coronary revascularization compared with medical therapy, but the choice of optimal revascularization technique is unresolved.   OBJECTIVE - To use bayesian methods to analyze the risk differences for patients with left main coronary artery disease randomized to treatment with coronary artery bypass surgery (C...

Clinical Impact of Valvular Heart Disease in Elderly Patients Admitted for Acute Coronary Syndrome: Insights From the Elderly-ACS 2 Study

Original Research | By G Crimi, C Montalto et al on behalf ofElderly-ACS 2 Investigators

BACKGROUND - Elderly patients are under-represented in clinical trials and registries, and a gap of evidence exists for clinical decision making in the setting of acute coronary syndromes (ACS). We aimed to assess the prevalence and independent prognostic impact of valvular heart disease (VHD) diagnosed during the index hospitalization on clinical outcomes among elderly patients with ACS. Included VHDs were moderate-to-severe...

In patients with stable coronary heart disease, low-density lipoprotein-cholesterol levels < 70 mg/dL and glycosylated hemoglobin A1c < 7% are associated with lower major cardiovascular events

Original Research | By HD White, RAH Stewart et al on behalf of the STABILITY Investigators

BACKGROUND - In patients with stable coronary heart disease, it is not known whether achievement of standard of care (SOC) targets in addition to evidence-based medicine (EBM) is associated with lower major adverse cardiovascular events (MACE): cardiovascular death, myocardial infarction, and stroke.   METHODS - EBM use was recommended in the STabilisation of Atherosclerotic plaque By Initiation of...

Cardiac Structural Changes After Transcatheter Aortic Valve Replacement: Systematic Review and Meta-Analysis of Cardiovascular Magnetic Resonance Studies

Original Research | By G Mehdipoor, S Chen, MR Prince et al.

Comparison of newer generation self-expandable vs. balloon-expandable valves in transcatheter aortic valve implantation: the randomized SOLVE-TAVI trial

Clinical Trial | By H Thiele, T Kurz et al on behalf of the SOLVE-TAVI Investigators.

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Original Research 785
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Clinical Case Study 28
Clinical Trial 415
Perspective 9
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2020 9
2019 1

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JAMA Cardiology 2
JACC: Cardiovascular Interventions 3
J Cardiovasc Magn Reson. 1
Eur Heart J. 1
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