ENGLISH
CBS2017
Previous Next
Home < 科学研究

搜索结果

数量：1763 条

排序

Refine search

Primary Prevention Trial Designs Using Coronary Imaging: A National Heart, Lung, and Blood Institute Workshop

Review Article | By P Greenland, ED Michos, N Redmond et al.

Coronary artery calcium (CAC) is considered a useful test for enhancing risk assessment in the primary prevention setting. Clinical trials are under consideration. The National Heart, Lung, and Blood Institute convened a multidisciplinary working group on August 26 to 27, 2019, in Bethesda, Maryland, to review available evidence and consider the appropriateness of conducting further research on coronary artery calcium (CAC) testing, or ot...

Mechanical circulatory support devices in advanced heart failure: 2020 and beyond

Review Article | By JL Vieira, HO Ventura, MR Mehra et al.

Substantial progress in the field of mechanical circulatory support (MCS) has expanded the treatment options for patients with advanced-stage heart failure (HF). Currently available MCS devices can be implanted percutaneously or surgically. They can also be configured to support the left, right, or both ventricles, offering varying levels of circulatory support. Short-term temporary MCS devices are primarily used in high-risk percutaneous ...

Role of endothelial dysfunction in determining angina after percutaneous coronary intervention: Learning from pathophysiology to optimize treatment

Review Article | By F Mangiacapraa; MGDel Buonobc; A Abbate et al.

Endothelial dysfunction (EnD) is a hallmark feature of coronary artery disease (CAD), representing the key early step of atherosclerotic plaque development and progression. Percutaneous coronary intervention (PCI) is performed daily worldwide to treat symptomatic CAD, however a consistent proportion of patients remain symptomatic for angina despite otherwise successful revascularization. EnD plays a central role in the mechanisms of ...

Implications of Alternative Definitions of Peri-Procedural Myocardial Infarction After Coronary Revascularization

Original Research | By J Gregson, GW Stone, SJ Pocock et al.

BACKGROUND - Numerous definitions for peri-procedural myocardial infarction (PMI) following percutaneous coronary intervention (PCI) and coronary bypass grafting (CABG) surgery exist.   OBJECTIVES - The purpose of this study was to investigate the PMI rates according to various definitions, their clinically relevant association with all-cause mortality at 10 years, and their impact on composite endpoints ...

SGLT2 Inhibitors in Patients With Heart Failure With Reduced Ejection Fraction: A Meta-Analysis of the EMPEROR-Reduced and DAPA-HF Trials

Review Article | By F Zannad, JP Ferreira, SJ Pocock et al.

BACKGROUND - Both DAPA-HF (assessing dapagliflozin) and EMPEROR-Reduced (assessing empagliflozin) trials showed that sodium-glucose co-transporter-2 (SGLT2) inhibition reduced the combined risk of cardiovascular death or hospitalisation for heart failure in patients with heart failure with reduced ejection fraction (HFrEF) with or without diabetes. However, neither trial was powered to assess effects on car...

Genotyping to Guide Clopidogrel Treatment: An In-Depth Analysis of the TAILOR-PCI Trial

Original Research | By Naveen L. Pereira, MBBS, FACC

Clopidogrel is the most widely prescribed P2Y12 inhibitor.1,2 It is a prodrug that requires CYP2C19, a cytochrome P450 enzyme, for transformation to its active thiol metabolite. Only this active metabolite targets the P2Y12 receptor on platelets, resulting in inhibition of platelet aggregation. Patients with CYP2C19 loss-of-function genetic variation (CYP2C19*2 and CYP2C19*3) have low active metabolite levels, less on-treatment pl...

Epidemiology and Clinical Outcomes of Patients With Inflammatory Bowel Disease Presenting With Acute Coronary Syndrome

Original Research | By G Pemmasani, I Elgendy, MA Mamas et al.

BACKGROUND - Inflammatory bowel disease (IBD) is associated with an increased acute coronary syndrome (ACS) risk. Data are limited regarding the epidemiology and outcomes of ACS in patients with IBD.   METHODS - A retrospective cohort analysis of patients with IBD admitted for ACS in the U.S. Healthcare Cost and Utilization Project National Inpatient Sample for 2005 to 2015 was conducted. ...

T and small protrusion (TAP) vs double kissing crush technique: Insights from in-vitro models

Original Research | By V Paradies, Jaryl Ng, HY Ang et al.

BACKGROUND - Percutaneous coronary interventions on complex bifurcation lesions may require implantation of two stents to appropriately treat diffuse side-branch (SB) disease. Comparisons among different bifurcation stenting techniques are continuously attempted by various study designs (bench tests, computer simulations, clinical studies). Among different techniques, double kissing crush (DKC) represents the last evolution for “...

State of the Art in Noninvasive Imaging of Ischemic Heart Disease and Coronary Microvascular Dysfunction in Women: Indications, Performance, and Limitations

Review Article | By P Koilpillai, NR Aggarwal, SL Mulvagh et al.

PURPOSE OF REVIEW - Establishing a diagnosis of ischemic heart disease (IHD) in women, including assessment for coronary microvascular dysfunction (CMD) when indicated, can be challenging. Access to performance of invasive testing when appropriate may be limited, and noninvasive imaging assessments have evolved. This review will summarize the various noninvasive imaging modalities available for the diagnosis of IHD and CMD...

Increased pulmonary serotonin transporter in patients with chronic obstructive pulmonary disease who developed pulmonary hypertension

Original Research | By A Frille, M Rullmann, S Hesse & HJ Seyfarth et al.

By Article Type

Original Research 785
Review Article 294
Clinical Case Study 28
Clinical Trial 415
Perspective 9
Guideline 50

By Year

2020 9
0 1

By Journal

Prog Cardiovasc Dis. 2
Lancet. 1
JACC Cardiovasc Imaging . 1
J Am Coll Cardiol. 1
Inflamm Bowel Dis. 1
Eur J Nucl Med Mol Imaging. 1
Curr Atheroscler Rep . 1
Cardiovasc Revasc Med. 1
ACC 1

Limit By

Title
Content
|<<... 138 139 140 141 142 143 144 ...>>|
↑BACK TO TOP

左主干暨冠状动脉分叉病变峰会

南京市心血管医院丨南京市第一医院丨南京医科大学

长乐路68号丨210006丨中国 · 南京

Copyright ⓒ CBSMD Nanjing China. All rights reserved.

关于境内代表注册有疑问请联系彭红娟、徐海梅老师

+86 - 139 138 954 77 丨 +86 - 139 147 368 46 丨 cbsnj@cbsmd.org

关于境外代表注册有疑问请联系林玲老师

+86 - 139 518 845 96 丨 cbsnj@cbsmd.org

关于学术征集有疑问请联系赵莹莹女士

+86 138 154 085 17 丨 sub@cbsmd.org