Clinical Trial | By Buccheri S, Franchina G, Capodanno D et al.
OBJECTIVES - The authors sought to explore the comparative clinical efficacy of different imaging modalities for guiding percutaneous coronary interventions (PCI). BACKGROUND - Coronary angiography (CA) is the standard imaging modality for intraprocedural guidance of PCI. Intracoronary imaging techniques, including intravascular ultrasound (IVUS) and optical co...
Clinical Trial | By Gobić D, Tomulić V, Lulić D et al.
BACKGROUND - Drug-eluting stents (DES) represent a significant evolution in the treatment of patients with acute myocardial infarction with ST elevation. However, stent-related adverse events have led to an introduction of drug-coated balloons (DCB) applied particularly to bifurcation lesions, in-stent restenosis and small vessel disease. The aim of this study was to determine whether a DCB-only strategy has...
Original Research | By Colleran R, Joner M, ISAR-DESIRE 3 and ISAR-DESIRE 4 investigators
BACKGROUND - Angioplasty with paclitaxel-coated balloons (PCB) is recommended for treatment of patients with coronary in-stent restenosis (ISR) according to European clinical practice guidelines. Most clinical trials have investigated iopromide-based PCB and there is a paucity of data comparing efficacy against butyryl-tri-hexyl citrate (BTHC)-based PCB. Our aim was to compare the performance of two widely-used ...
New AHA/ACC/HRS Guidance on Sudden Cardiac Death Prevention
Guideline | By Sana M. Al-Khatib, W.G. Stevenson, M.J. Ackerman et al.
Original Research | By Zheng X, Curtis JP, China PEACE Collaborative Group
IMPORTANCE - The use of coronary catheterization and percutaneous coronary intervention (PCI) is increasing in China, but, to date, there are no nationally representative assessments of the quality of care and outcomes in patients undergoing these procedures. OBJECTIVE - To assess the quality of care and outcomes of patients undergoing coronary catheterization and&...
Original Research | By Yudi MB, Hamilton G, Melbourne Interventional Group
Guidelines strongly recommend patients with ST-elevation myocardial infarction (STEMI) receive timely mechanical reperfusion, defined as door-to-balloon time (DTBT) ≤90 minutes. The impact of timely reperfusion on clinical outcomes in patients aged 75-84 and ≥85 years is uncertain. We analysed 2,972 consecutive STEMI patients who underwent primary percutaneous coronary intervention from the Melbourne Interventional Group Registry (2005-...
Original Research | By Mentias A, Raza MQ, Kapadia SR et al.
Cardiovascular disease remains the most common cause of mortality. We studied the change in outcomes for anterior ST-elevation myocardial infarction (STEMI) between 1995 and 2014. Over the past 20 years, 1,658 patients presenting to our center with anterior STEMI underwent primary percutaneous coronary intervention within 12 hours of presentation. We divided these into 4 quartiles, 1995 to 1999 (n = 312), 2000 to 2...
Original Research | By Selker HP, Udelson JE, Ruthazer R et al.
BACKGROUND - While infarct size in patients with ST-segment elevation myocardial infarction (STEMI) has been generally associated with long-term prognosis, whether a therapeutic effect on infarct size has a corresponding therapeutic effect on long-term outcomes is unknown. METHODS - Using combined patient-level data from 10 randomized trials of primary percutaneous coronary intervention (PCI) for STEMI, we cr...
Original Research | By Lee WC, Fang HY, Fang CY et al.
OBJECTIVE - Few studies have focused on the effects of an improved door-to-balloon time on clinical outcomes in patients with ST-segment elevation myocardial infarction (STEMI). The aim of this study was to explore the effect of improving door-to-balloon time on prognosis and to identify major predictors of mortality. METHODS - From January 2005 to December 2014, 1751 patients experienced STEMI and received...
Clinical Case Study | By Thim T, Götberg M, Fröbert O et al.
OBJECTIVES - The aim of this study was to examine the level of agreement between acute instantaneous wave-free ratio (iFR) measured across nonculprit stenoses in patients with ST-segment elevation myocardial infarction (STEMI) and iFR measured at a staged follow-up procedure. BACKGROUND - Acute full revascularization of nonculprit stenoses in STEMI is debated and currently guided by angiography. Acute fun...