Original Research | By Arbel Y, Bennell MC, Wijeysundera HC et al.
BACKGROUND - There is uncertainty regarding the optimal duration of dual-antiplatelet therapy (DAPT) after percutaneous coronary intervention (PCI). Our goal was to evaluate the cost-effectiveness of different durations of DAPT. METHODS - We created a probabilistic patient-level Markov microsimulation model to assess the discounted lifetime costs and quality-adjusted life years (QALYs) of short&...
Review Article | By Gupta A, Bajaj NS, Bhatt DL et al.
BACKGROUND - Randomized controlled trials (RCTs) have shown fractional flow reserve-guided (FFR) multivessel stenting to be superior to infarct-related artery (IRA) only stenting in patients with ST-elevation myocardial infarction (STEMI) and multivessel disease. This effect was mainly driven by a reduction in overall repeat revascularization. However, the ability to assess the effect of this strategy on urgent ...
Review Article | By Kiaos A, Tziatzios I, Karamitsos TD et al.
INTRODUCTION - The purpose of this study was to investigate the accuracy of qualitative stress perfusion cardiac magnetic resonance (CMR) to diagnose ischemia-causing lesions according to different definitions of significant coronary artery disease (CAD), and magnetic field strength. METHODS - We searched PubMed, Web of Science, and the Cochrane Library for studies evaluating diagnostic performance of qualitative stre...
Clinical Case Study | By Kodaira M, Tabei R, Kuno T et al.
A 46-year-old man underwent coronary angiography for stable angina. He developed inferior ST-segment myocardial infarction during the angiography. Intravascular ultrasound (IVUS) findings suggested coronary vasospasm. Intracoronary administration of isosorbide dinitrate restored the coronary flow. This case illustrates the essential role IVUS imaging played in establishing the diagnosis of catheter-induced coronary vasospasm.
Clinical Trial | By Sotomi Y, Onuma Y, Dijkstra J et al.
AIMS - The natural course of post-procedural incomplete strut apposition (ISA) after the implantation of bioresorbable scaffolds (BVS) remains unknown. The purpose of the present study was to evaluate the fate of post-procedural ISA after everolimus-eluting Absorb BVS in comparison with the second-generation everolimus-eluting cobalt chromium stent (CoCr-EES). METHODS AND RESULTS - Fate of post-procedura...
Perspective | By Wijns W, Shite J, Jones MR et al.
AIMS - ILUMIEN I is the largest prospective, non-randomized, observational study of percutaneous coronaryintervention (PCI) procedural practice in patients undergoing intra-procedural pre- and post-PCI fractional flow reserve (FFR) and optical coherence tomography (OCT). We report on the impact of OCT on physician decision-making and the association with post-PCI FFR values and early clinical events. M...
Intracoronary Optical Coherence Tomography 2018: Current Status and Future Directions
Review Article | By Ali ZA, Karimi Galougahi K, Maehara A et al.
The advent of intravascular imaging has been a significant advancement in visualization of coronary arteries, particularly with optical coherence tomography (OCT) that allows for high-resolution imaging of intraluminal and transmural coronary structures. Accumulating data support a clinical role for OCT in a multitude of clinical scenarios, including assessing the natural history of atherosclerosis and modulating effects of therap...
Clinical Trial | By Ali ZA, Stone GW; ILUMIEN III: OPTIMIZE PCI Investigators.
BACKGROUND - Percutaneous coronary intervention (PCI) is most commonly guided by angiography alone. Intravascular ultrasound (IVUS) guidance has been shown to reduce major adverse cardiovascular events (MACE) after PCI, principally by resulting in a larger postprocedure lumen than with angiographic guidance. Optical coherence tomography (OCT) provides higher resolution imaging than does IVUS, although findings from some studie...
Original Research | By Maehara A, Ben-Yehuda O, Stone GW et al.
OBJECTIVES - The present study sought to determine whether optical coherence tomography (OCT) guidance results in a degree of stent expansion comparable to that with intravascular ultrasound (IVUS) guidance. BACKGROUND - The most important predictor of adverse outcomes (thrombosis and restenosis) after stent implantation with IVUS guidance is the degree of stent expansion achieved. M...